{"id":"montelukast","rwe":[],"tags":[],"phase":"marketed","safety":{"boxedWarnings":[],"safetySignals":[],"drugInteractions":[],"commonSideEffects":[{"effect":"Upper respiratory infection","drugRate":"","severity":"common","organSystem":""},{"effect":"Fever","drugRate":"","severity":"common","organSystem":""},{"effect":"Headache","drugRate":"","severity":"common","organSystem":""},{"effect":"Pharyngitis","drugRate":"","severity":"common","organSystem":""},{"effect":"Cough","drugRate":"","severity":"common","organSystem":""},{"effect":"Abdominal pain","drugRate":"","severity":"common","organSystem":""},{"effect":"Diarrhea","drugRate":"","severity":"common","organSystem":""},{"effect":"Otitis media","drugRate":"","severity":"common","organSystem":""},{"effect":"Influenza","drugRate":"","severity":"common","organSystem":""},{"effect":"Rhinorrhea","drugRate":"","severity":"common","organSystem":""},{"effect":"Sinusitis","drugRate":"","severity":"common","organSystem":""},{"effect":"Otitis","drugRate":"","severity":"common","organSystem":""}],"contraindications":["Anxiety","Depressive disorder","Dream disorder","Eosinophil count raised","Feeling agitated","Hallucinations","Mood swings","Nervousness","Suicidal thoughts","Tremors","Vasculitis of the skin"],"specialPopulations":{},"discontinuationRates":[],"seriousAdverseEvents":[{"effect":"Neuropsychiatric events","drugRate":"","severity":"serious"}]},"status":"approved","trials":["NCT02322671","NCT00656058","NCT01089647","NCT04270409","NCT00974571","NCT00394355","NCT00802789","NCT00446056","NCT00157937","NCT00406094","NCT00351364","NCT02479854","NCT01241084","NCT01759472","NCT06429475","NCT05852769","NCT04621513","NCT01928056","NCT01027806","NCT00524693","NCT04294459","NCT00934713","NCT02227173","NCT05143502","NCT04714515","NCT00116324","NCT00148408","NCT00379808","NCT04080089","NCT00783601","NCT00557284","NCT01140048","NCT07101640","NCT00756418","NCT02505113","NCT00676468","NCT02906670","NCT05447520","NCT02658422","NCT00819676","NCT01248975","NCT00513760","NCT01086527","NCT01404013","NCT04957927","NCT00127647","NCT01211509","NCT00385463","NCT02110654","NCT05607446"],"aliases":["Singulair"],"patents":[],"pricing":[],"allNames":"singulair","offLabel":[],"timeline":[],"aiSummary":"Montelukast (Singulair) is the most prescribed leukotriene receptor antagonist, developed by Merck and approved in 1998. 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