{"id":"monoxerutin","rwe":[{"pmid":"38706885","year":"2024","title":"The artificial neural network selects saccharides from natural sources a promise for potential FimH inhibitor to prevent UTI infections.","finding":"","journal":"In silico pharmacology","studyType":"Clinical Study"}],"tags":[{"label":"Small Molecule","category":"modality"},{"label":"C05CA02","category":"atc"},{"label":"Active","category":"status"},{"label":"Peripheral venous insufficiency","category":"indication"}],"phase":"phase_2","safety":{},"trials":[],"aliases":[],"patents":[],"pricing":[],"allNames":["monoxerutin"],"offLabel":[],"synonyms":["monoxerutin"],"timeline":[],"approvals":[],"ecosystem":[{"indication":"Peripheral venous insufficiency","otherDrugs":[],"globalPrevalence":null}],"mechanism":{"modality":"Small Molecule","explanation":"Imagine your blood vessels are like roads in your body. When they get damaged or weakened, it's harder for blood to flow through them. Monoxerutin helps to fix these roads by improving their function and reducing inflammation, which can help to alleviate symptoms of peripheral venous insufficiency.","oneSentence":"Monoxerutin works by improving blood vessel function and reducing inflammation.","technicalDetail":"Monoxerutin is believed to exert its effects through antioxidant and anti-inflammatory mechanisms, potentially involving the inhibition of certain enzymes and the modulation of signaling pathways involved in vascular function."},"commercial":{},"references":[{"id":1,"url":"https://drugcentral.org/drugcard/1835","fields":["approvals","synonyms","ATC","PK","indications","contraindications","DDIs","targets","patents","FAERS"],"source":"DrugCentral"},{"id":2,"url":"https://pubmed.ncbi.nlm.nih.gov/?term=MONOXERUTIN","fields":["publications"],"source":"PubMed/NCBI"}],"_enrichedAt":"2026-03-30T14:34:00.223946","biosimilars":[],"competitors":[],"genericName":"monoxerutin","indications":{"approved":[{"name":"Peripheral venous insufficiency","source":"DrugCentral","snomedId":20696009,"regulator":"FDA"}],"offLabel":[],"pipeline":[]},"drugCategory":"active","labelChanges":[],"relatedDrugs":[],"trialDetails":[],"genericFilers":[],"latestUpdates":[],"manufacturing":[],"crossReferences":{"NDDF":"006547","UNII":"EKF7043SBU","INN_ID":"3669","UMLSCUI":"C0771957","ChEMBL_ID":"CHEMBL3527416","KEGG_DRUG":"D07179","DRUGBANK_ID":"DB13764","PUBCHEM_CID":"9852585"},"formularyStatus":[],"_enricherVersion":"v2","developmentCodes":[],"ownershipHistory":[],"publicationCount":1,"therapeuticAreas":["Hematology"],"atcClassification":{"source":"DrugCentral","atcCode":"C05CA02","allCodes":["C05CA02"]},"biosimilarFilings":[],"recentPublications":[{"date":"2024","pmid":"38706885","title":"The artificial neural network selects saccharides from natural sources a promise for potential FimH inhibitor to prevent UTI infections.","journal":"In silico pharmacology"}],"companionDiagnostics":[],"genericManufacturerList":[],"status":"active","brandName":"MONOXERUTIN","companyName":"","companyId":"","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Monoxerutin is a small molecule drug with unknown drug class and target. It is used to treat peripheral venous insufficiency, a condition characterized by weakened veins that can lead to swelling and pain. The commercial status of Monoxerutin is unclear, and it is not known if it is patented or available as a generic. Further information on its pharmacokinetics, safety, and efficacy is needed. As a treatment for peripheral venous insufficiency, Monoxerutin is likely to be used in conjunction with other therapies to manage symptoms and prevent complications.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"partial","dataCompleteness":{"mechanism":true,"indications":true,"safety":false,"trials":false,"score":2}}