{"id":"mometasone-furoate-50-micrograms","safety":{"commonSideEffects":[{"rate":null,"effect":"Headache"},{"rate":null,"effect":"Pharyngitis"},{"rate":null,"effect":"Epistaxis"},{"rate":null,"effect":"Nasal irritation"},{"rate":null,"effect":"Dysphonia"},{"rate":null,"effect":"Oral candidiasis (with inhaled formulation)"}]},"_chembl":{"chemblId":"CHEMBL1161","moleculeType":"Small molecule","molecularWeight":"521.44"},"_fixedAt":"2026-03-30T18:05:07.702055","_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"Mometasone furoate is a potent synthetic glucocorticoid that exerts anti-inflammatory effects through activation of glucocorticoid receptors in target tissues. This leads to decreased production of pro-inflammatory cytokines, chemokines, and adhesion molecules, thereby reducing inflammation and immune cell infiltration. It is commonly used as a topical or inhaled agent for localized anti-inflammatory effects.","oneSentence":"Mometasone furoate is a corticosteroid that suppresses inflammatory and immune responses by binding to glucocorticoid receptors and reducing the production of inflammatory mediators.","_ai_confidence":"high"},"_scrapedAt":"2026-03-28T01:21:57.243Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Allergic rhinitis"},{"name":"Asthma"},{"name":"Chronic obstructive pulmonary disease (COPD)"},{"name":"Inflammatory skin conditions"}]},"_fixedFields":["pubmed(1)"],"trialDetails":[],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":1,"recentPublications":[{"date":"1997 Jul","pmid":"9236500","title":"Dose ranging study of mometasone furoate (Nasonex) in seasonal allergic rhinitis.","journal":"Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology"}],"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":["NASONEX®"],"phase":"phase_3","status":"active","brandName":"Mometasone furoate 50 micrograms","genericName":"Mometasone furoate 50 micrograms","companyName":"Sanofi","companyId":"sanofi","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Mometasone furoate is a corticosteroid that suppresses inflammatory and immune responses by binding to glucocorticoid receptors and reducing the production of inflammatory mediators. Used for Allergic rhinitis, Asthma, Chronic obstructive pulmonary disease (COPD).","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":1,"withResults":1},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":false,"score":3}}