{"id":"mob015b","safety":{"commonSideEffects":[{"rate":null,"effect":"Application site irritation"},{"rate":null,"effect":"Nail discoloration"},{"rate":null,"effect":"Contact dermatitis"}]},"_chembl":null,"_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"MOB015B is a nail lacquer formulation developed for onychomycosis (fungal nail infection) treatment. The drug works by delivering antifungal activity directly to infected nail tissue, with the goal of improving nail penetration and efficacy compared to existing topical treatments. It is being evaluated in phase 3 clinical trials for moderate-to-severe toenail onychomycosis.","oneSentence":"MOB015B is a topical antimicrobial agent designed to treat fungal nail infections by inhibiting fungal growth and promoting nail clearance.","_ai_confidence":"medium"},"_scrapedAt":"2026-03-28T01:21:50.312Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Onychomycosis (fungal nail infection)"}]},"trialDetails":[{"nctId":"NCT05279846","phase":"PHASE3","title":"A Vehicle-controlled Study of Topical MOB015B in the Treatment of Distal Subungual Onychomycosis (DSO)","status":"ACTIVE_NOT_RECRUITING","sponsor":"Moberg Pharma AB","startDate":"2022-05-09","conditions":"Onychomycosis","enrollment":350},{"nctId":"NCT06369727","phase":"PHASE1","title":"Study to Evaluate the Sensitizing Potential of MOB015B in Healthy Subjects Using a Repeat Insult Patch Test Design","status":"COMPLETED","sponsor":"Moberg Pharma AB","startDate":"2017-10-15","conditions":"Erythema","enrollment":250},{"nctId":"NCT06369675","phase":"PHASE1","title":"Skin Irritation Potential of MOB015B in Healthy Subjects Using a Cumulative Irritant Patch Test Design","status":"COMPLETED","sponsor":"Moberg Pharma AB","startDate":"2017-10-19","conditions":"Erythema","enrollment":45},{"nctId":"NCT02859519","phase":"PHASE3","title":"A Multi-centre, Double-blind, Randomized, Vehicle-controlled Study of Efficacy and Safety of Topical MOB015B in the Treatment of Mild to Moderate Distal Subungual Onychomycosis (DSO)","status":"COMPLETED","sponsor":"Moberg Pharma AB","startDate":"2016-10","conditions":"Distal Subungual Onychomycosis","enrollment":365},{"nctId":"NCT02866032","phase":"PHASE3","title":"Study to Evaluate the Efficacy and Safety of Topical MOB015B in the Treatment of Mild to Moderate Distal Subungual Onychomycosis (DSO)","status":"COMPLETED","sponsor":"Moberg Pharma AB","startDate":"2016-09","conditions":"Distal Subungual Onychomycosis","enrollment":452},{"nctId":"NCT03244280","phase":"PHASE1","title":"A Study of the Systemic Absorption of MOB015B","status":"COMPLETED","sponsor":"Moberg Pharma AB","startDate":"2017-12-16","conditions":"Onychomycosis","enrollment":20},{"nctId":"NCT01814020","phase":"PHASE2","title":"An Open,Single-centre Pilot Study of Efficacy and Safety of Topical MOB015B in the Treatment of Distal Subungual Onychomycosis (DSO)","status":"COMPLETED","sponsor":"Moberg Pharma AB","startDate":"2012-12","conditions":"Distal Subungual Onychomycosis","enrollment":""}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":1,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":[],"phase":"phase_3","status":"active","brandName":"MOB015B","genericName":"MOB015B","companyName":"Moberg Pharma AB","companyId":"moberg-pharma-ab","modality":"Small molecule","firstApprovalDate":"","aiSummary":"MOB015B is a topical antimicrobial agent designed to treat fungal nail infections by inhibiting fungal growth and promoting nail clearance. Used for Onychomycosis (fungal nail infection).","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":1,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}