{"id":"mmrv-amp","safety":{"commonSideEffects":[{"rate":"20-30","effect":"Injection site reactions (erythema, swelling, pain)"},{"rate":"15-20","effect":"Fever"},{"rate":"3-5","effect":"Rash"},{"rate":"1-2","effect":"Varicella-like rash"},{"rate":"<1","effect":"Parotitis"}]},"_chembl":{"chemblId":"CHEMBL4297570","moleculeType":"Unknown"},"_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"MMRV combines four live attenuated viral vaccines into a single formulation. Each component virus is weakened to trigger protective antibody and cell-mediated immune responses without causing disease. The vaccine primes the immune system to recognize and rapidly respond to natural infection with any of these four viruses.","oneSentence":"MMRV is a live attenuated combination vaccine that provides immunization against measles, mumps, rubella, and varicella by stimulating adaptive immune responses to all four viruses.","_ai_confidence":"high"},"_scrapedAt":"2026-03-28T01:21:50.378Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Prevention of measles, mumps, rubella, and varicella in children"}]},"trialDetails":[{"nctId":"NCT01536405","phase":"PHASE3","title":"Safety, Tolerability, and Immunogenicity of Measles, Mumps, Rubella, and Varicella (MMRV) Vaccine Made With an Alternative Manufacturing Process (AMP)(V221-027)","status":"COMPLETED","sponsor":"Merck Sharp & Dohme LLC","startDate":"2012-06-05","conditions":"Measles, Mumps, Rubella","enrollment":1412}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":1,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":[],"phase":"phase_3","status":"active","brandName":"MMRV (AMP)","genericName":"MMRV (AMP)","companyName":"Merck Sharp & Dohme LLC","companyId":"merck","modality":"Biologic","firstApprovalDate":"","aiSummary":"MMRV is a live attenuated combination vaccine that provides immunization against measles, mumps, rubella, and varicella by stimulating adaptive immune responses to all four viruses. Used for Prevention of measles, mumps, rubella, and varicella in children.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}