{"id":"mixture-of-three-bifidobacteria","safety":{"commonSideEffects":[{"rate":null,"effect":"Gastrointestinal disturbance"},{"rate":null,"effect":"Bloating"},{"rate":null,"effect":"Flatulence"}]},"_chembl":{"chemblId":"CHEMBL3142645","moleculeType":"Small molecule","molecularWeight":"2553.11"},"_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"Bifidobacteria are commensal bacteria that colonize the colon and produce short-chain fatty acids, particularly butyrate, which strengthen the intestinal barrier, reduce pathogenic bacterial overgrowth, and modulate local and systemic immune responses. This probiotic mixture aims to restore eubiotic balance in dysbiotic conditions, improving gastrointestinal symptoms and potentially enhancing overall health outcomes.","oneSentence":"A mixture of three Bifidobacteria strains restores beneficial gut microbiota composition to promote intestinal health and immune function.","_ai_confidence":"low"},"_scrapedAt":"2026-03-27T23:55:27.067Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Dysbiosis and gastrointestinal disorders (specific indications not fully characterized in available literature)"}]},"trialDetails":[{"nctId":"NCT02566876","phase":"PHASE4","title":"Bifidobacteria In Children With Abdominal Pain-Associated Functional Gastrointestinal Disorders","status":"COMPLETED","sponsor":"Federico II University","startDate":"2013-12","conditions":"Irritable Bowel Syndrome, Dyspepsia Chronic","enrollment":73}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":0,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":["Bifidobacterium infantis M-63® breve M-16V® longum BB536®"],"phase":"marketed","status":"active","brandName":"Mixture of three Bifidobacteria","genericName":"Mixture of three Bifidobacteria","companyName":"Federico II University","companyId":"federico-ii-university","modality":"Small molecule","firstApprovalDate":"","aiSummary":"A mixture of three Bifidobacteria strains restores beneficial gut microbiota composition to promote intestinal health and immune function. Used for Dysbiosis and gastrointestinal disorders (specific indications not fully characterized in available literature).","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}