{"id":"mitomycin-c-0-02","safety":{"commonSideEffects":[{"rate":null,"effect":"Corneal toxicity"},{"rate":null,"effect":"Conjunctival scarring"},{"rate":null,"effect":"Epithelial defects"},{"rate":null,"effect":"Iritis/uveitis"}]},"_chembl":null,"_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"Mitomycin C acts as a prodrug that is activated in cells to form reactive intermediates capable of covalently binding to DNA and creating interstrand cross-links. This DNA damage triggers cell cycle arrest and programmed cell death, making it effective against cancer cells and proliferating tissues. 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Used for Prevention of conjunctival and corneal scarring following ocular surgery, Adjunctive therapy in glaucoma filtration surgery, Prevention of pterygium recurrence.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}