{"id":"misoprostol-per-oral-tablets","safety":{"commonSideEffects":[{"rate":"13–40","effect":"Diarrhea"},{"rate":"7–20","effect":"Abdominal pain"},{"rate":"3–7","effect":"Nausea"},{"rate":"2–5","effect":"Dyspepsia"},{"rate":null,"effect":"Uterine contractions (when used for labor induction)"}]},"_chembl":{"chemblId":"CHEMBL4064157","moleculeType":"Small molecule","molecularWeight":"382.54"},"_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"Misoprostol acts as a synthetic prostaglandin analogue that activates EP3 and other prostaglandin receptors on gastric mucosa. This stimulates mucus and bicarbonate secretion while simultaneously reducing gastric acid production, thereby protecting the gastric lining. It is commonly used to prevent nonsteroidal anti-inflammatory drug (NSAID)-induced ulcers and is also employed for cervical ripening and labor induction due to its uterotonic effects.","oneSentence":"Misoprostol is a prostaglandin E1 analogue that binds to prostaglandin receptors to increase gastric mucus production and reduce gastric acid secretion.","_ai_confidence":"high"},"_scrapedAt":"2026-03-27T23:55:21.411Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Prevention of NSAID-induced gastric ulcers"},{"name":"Treatment of gastric ulcers"},{"name":"Cervical ripening and labor induction"}]},"trialDetails":[{"nctId":"NCT07422506","phase":"NA","title":"A Real-World Study Comparing the Efficacy of Different Treatment Regimens for Early Missed Abortion","status":"RECRUITING","sponsor":"The Third Xiangya Hospital of Central South University","startDate":"2024-01-01","conditions":"Missed Abortion, Early Pregnancy 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Used for Prevention of NSAID-induced gastric ulcers, Treatment of gastric ulcers, Medical abortion (in combination with mifepristone).","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}