{"id":"minoxidil-topical-foam","safety":{"commonSideEffects":[{"rate":null,"effect":"Scalp irritation"},{"rate":null,"effect":"Pruritus"},{"rate":null,"effect":"Erythema"},{"rate":null,"effect":"Dryness"},{"rate":null,"effect":"Hypertrichosis (unwanted hair growth)"}]},"_chembl":null,"_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"Minoxidil acts as a vasodilator by opening ATP-sensitive potassium channels, which increases cutaneous blood flow to hair follicles and delivers more oxygen and nutrients to promote hair growth. It also directly stimulates hair follicle growth and extends the duration of the anagen phase, shifting hairs from telogen (resting) to anagen (active growth) phase. The topical foam formulation allows for direct application to the scalp with improved absorption and patient compliance.","oneSentence":"Minoxidil is a potassium channel opener that increases blood flow to hair follicles and prolongs the anagen (growth) phase of the hair cycle.","_ai_confidence":"high"},"_scrapedAt":"2026-03-28T01:21:34.234Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Androgenetic alopecia (male pattern baldness)"},{"name":"Hair loss in women"}]},"trialDetails":[{"nctId":"NCT05417308","phase":"EARLY_PHASE1","title":"Topical or Oral Minoxidil for the Treatment of Endocrine Therapy-Induced Alopecia in Patients With Stage I-IV Breast Cancer","status":"RECRUITING","sponsor":"Ohio State University Comprehensive Cancer Center","startDate":"2023-03-01","conditions":"Anatomic Stage I Breast Cancer AJCC v8, Anatomic Stage IA Breast Cancer AJCC v8, Anatomic Stage IB Breast Cancer AJCC v8","enrollment":50},{"nctId":"NCT07076706","phase":"PHASE2","title":"Clinical Trial to Evaluate CG2001 in Chinese Adult Male Participants With Androgenetic Alopecia","status":"COMPLETED","sponsor":"Beijing Dayspring Pharmaceutical Technology Co., Ltd","startDate":"2024-12-05","conditions":"Male Pattern of Hair Loss, Androgenic Alopecia, Androgenetic Alopecia (AGA)","enrollment":110},{"nctId":"NCT04207931","phase":"PHASE4","title":"Treatment Results for Patients With Central Centrifugal Cicatricial Alopecia (CCCA): a Multicenter Prospective Study","status":"RECRUITING","sponsor":"Wake Forest University Health Sciences","startDate":"2018-04-30","conditions":"Central Centrifugal Cicatricial Alopecia (CCCA)","enrollment":250},{"nctId":"NCT04721548","phase":"PHASE3","title":"Treatment of Androgenetic Alopecia in Men for 24 Weeks","status":"COMPLETED","sponsor":"Eurofarma Laboratorios S.A.","startDate":"2023-03-02","conditions":"Alopecia","enrollment":336},{"nctId":"NCT03488108","phase":"PHASE1, PHASE2","title":"Platelet Rich Plasma Versus Minoxidil Foam for Treatment of Androgenic Alopecia in Women","status":"COMPLETED","sponsor":"Mayo Clinic","startDate":"2017-01-23","conditions":"Alopecia","enrollment":20},{"nctId":"NCT02206802","phase":"","title":"Minoxidil Response Testing in Females With Female Pattern Hair Loss","status":"COMPLETED","sponsor":"Applied Biology, Inc.","startDate":"2014-07","conditions":"Alopecia, Female Pattern Hair Loss","enrollment":300},{"nctId":"NCT02198261","phase":"","title":"Minoxidil Response Testing in Males With Androgenetic Alopecia","status":"COMPLETED","sponsor":"Applied Biology, Inc.","startDate":"2014-07","conditions":"Androgenetic Alopecia","enrollment":300},{"nctId":"NCT00151515","phase":"PHASE3","title":"A Study to Evaluate the Effectiveness and Safety of 5 Percent Minoxidil Foam in the Treatment of Male Pattern Hair Loss","status":"COMPLETED","sponsor":"Johnson & Johnson Consumer and Personal Products Worldwide","startDate":"2003-10","conditions":"Androgenetic Alopecia","enrollment":352},{"nctId":"NCT01226459","phase":"PHASE3","title":"Clinical Trial in Females for Female Pattern Hair Loss","status":"COMPLETED","sponsor":"Johnson & Johnson Healthcare Products Division of McNEIL-PPC, Inc.","startDate":"2010-09","conditions":"Androgenetic Alopecia","enrollment":404},{"nctId":"NCT01145625","phase":"PHASE3","title":"Clinical Trial in Females With Female Pattern Hair Loss","status":"COMPLETED","sponsor":"Johnson & Johnson Healthcare Products Division of McNEIL-PPC, Inc.","startDate":"2010-06","conditions":"Alopecia","enrollment":322},{"nctId":"NCT01319370","phase":"PHASE2","title":"Effectiveness and Safety of Minoxidil Foam Versus Placebo Foam for Androgenetic Alopecia","status":"COMPLETED","sponsor":"Natalie GARCIA BARTELS","startDate":"2010-11","conditions":"Androgenetic Alopecia","enrollment":70},{"nctId":"NCT00958750","phase":"PHASE3","title":"Efficacy and Safety Study to Compare Two Minoxidil Formulations on Women With Androgenetic Alopecia","status":"COMPLETED","sponsor":"Charite University, Berlin, Germany","startDate":"2008-06","conditions":"Androgenetic Alopecia, Female Pattern Hair Loss","enrollment":113}],"_emaApprovals":[],"_faersSignals":[{"count":1,"reaction":"ALOPECIA"},{"count":1,"reaction":"DANDRUFF"},{"count":1,"reaction":"EMOTIONAL DISTRESS"},{"count":1,"reaction":"FOLLICULITIS"},{"count":1,"reaction":"PARADOXICAL DRUG REACTION"}],"_approvalHistory":[],"publicationCount":10,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":[],"phase":"phase_3","status":"active","brandName":"Minoxidil Topical Foam","genericName":"Minoxidil Topical Foam","companyName":"Eurofarma Laboratorios S.A.","companyId":"eurofarma-laboratorios-s-a","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Minoxidil Topical Foam is used to treat Male Pattern of Hair Loss, specifically Androgenetic Alopecia (AGA), as indicated by ClinicalTrials.gov. It works as a Sulfonylurea receptor 2, Kir6.2 opener, a mechanism of action verified by ChEMBL.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":1,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}