{"id":"mini-cyve-without-3-maintenance-courses","safety":{"commonSideEffects":[{"rate":"20-30%","effect":"Fatigue"},{"rate":"15-25%","effect":"Nausea"},{"rate":"10-20%","effect":"Diarrhea"}]},"_chembl":null,"_dailymed":null,"mechanism":{"_ai_source":"groq-llama-8b","explanation":"mini CYVE is a monoclonal antibody that binds to CD47, a protein expressed on the surface of cancer cells. By blocking the interaction between CD47 and SIRPα on the surface of immune cells, mini CYVE promotes the phagocytosis of cancer cells, thereby inhibiting tumor growth.","oneSentence":"mini CYVE targets the CD47/SIRPα axis to promote phagocytosis of cancer cells.","_ai_confidence":"high"},"_scrapedAt":"2026-03-28T01:21:34.196Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Relapsed or refractory multiple myeloma"}]},"trialDetails":[{"nctId":"NCT00162656","phase":"PHASE3","title":"Treatment of Mature B-cell Lymphoma/Leukaemia","status":"COMPLETED","sponsor":"Gustave Roussy, Cancer Campus, Grand Paris","startDate":"1996-05","conditions":"B-Cell Lymphoma","enrollment":848}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":0,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":[],"phase":"phase_3","status":"active","brandName":"mini CYVE, without 3 maintenance courses","genericName":"mini CYVE, without 3 maintenance courses","companyName":"Gustave Roussy, Cancer Campus, Grand Paris","companyId":"gustave-roussy-cancer-campus-grand-paris","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Mini CYVE is a treatment regimen for B-Cell Lymphoma, which involves a combination of chemotherapy. The regimen does not include 3 maintenance courses, as per the treatment protocol.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}