{"id":"minhai-hib","safety":{"commonSideEffects":[{"rate":null,"effect":"Injection site reactions (erythema, swelling, pain)"},{"rate":null,"effect":"Fever"},{"rate":null,"effect":"Irritability"},{"rate":null,"effect":"Drowsiness"}]},"_chembl":null,"_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"The vaccine consists of the Hib polysaccharide conjugated to a protein carrier, which enhances immunogenicity and promotes T-cell dependent B-cell responses. This generates both antibody and cellular immunity against H. influenzae type b, preventing invasive bacterial infections including meningitis, bacteremia, and epiglottitis.","oneSentence":"Minhai-HIB is a Haemophilus influenzae type b (Hib) conjugate vaccine that stimulates immune responses against the polysaccharide capsule of H. influenzae type b bacteria.","_ai_confidence":"medium"},"_scrapedAt":"2026-03-28T01:21:27.142Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Prevention of invasive Haemophilus influenzae type b disease in infants and children"}]},"trialDetails":[{"nctId":"NCT02560272","phase":"PHASE3","title":"Safety and Immunogenicity of Haemophilus Influenzae Type b Conjugate Vaccine，Freeze-dried","status":"UNKNOWN","sponsor":"Beijing Minhai Biotechnology Co., Ltd","startDate":"2014-09","conditions":"Haemophilus Influenzae Type b Infections","enrollment":1560}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":0,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":[],"phase":"phase_3","status":"active","brandName":"Minhai-HIB","genericName":"Minhai-HIB","companyName":"Beijing Minhai Biotechnology Co., Ltd","companyId":"beijing-minhai-biotechnology-co-ltd","modality":"Biologic","firstApprovalDate":"","aiSummary":"Minhai-HIB is a Haemophilus Influenzae Type b conjugate vaccine that has been studied in a Phase III clinical trial. The vaccine was tested for safety and immunogenicity in a double-blind, parallel-controlled, randomized study.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}