{"id":"milverine","rwe":[{"pmid":"3770157","year":"1986","title":"Milverine: in vitro and in vivo activity on the animal and human colon.","finding":"","journal":"Il Farmaco; edizione pratica","studyType":"Clinical Study"}],"tags":[{"label":"milverine","category":"class"},{"label":"Small Molecule","category":"modality"},{"label":"Active","category":"status"}],"phase":"phase_2","safety":{},"trials":[],"aliases":[],"patents":[],"pricing":[],"allNames":"fenpyramine","offLabel":[],"synonyms":["milverine hydrochloride","fenpyramine hydrochloride","fenpyramine","milverine"],"timeline":[],"approvals":[],"brandName":"Fenpyramine","ecosystem":[],"mechanism":{"modality":"Small Molecule","drugClass":"milverine","explanation":"Imagine your body has a system that helps you feel pain. Fenpyramine is thought to interact with this system in some way, but we don't know exactly how. This interaction may help reduce the amount of pain you feel.","oneSentence":"Fenpyramine is believed to affect the body's response to pain, although its exact mechanism of action is unknown.","technicalDetail":"The exact mechanism of action of Fenpyramine is unknown, but it is believed to involve modulation of the body's pain response pathways, possibly through interaction with opioid or other receptors."},"commercial":{},"references":[{"id":1,"url":"https://drugcentral.org/drugcard/3996","fields":["approvals","synonyms","ATC","PK","indications","contraindications","DDIs","targets","patents","FAERS"],"source":"DrugCentral"},{"id":2,"url":"https://pubmed.ncbi.nlm.nih.gov/?term=MILVERINE","fields":["publications"],"source":"PubMed/NCBI"}],"_enrichedAt":"2026-03-30T15:03:30.688987","biosimilars":[],"competitors":[],"genericName":"milverine","indications":{"approved":[],"offLabel":[],"pipeline":[]},"drugCategory":"active","labelChanges":[],"relatedDrugs":[],"trialDetails":[],"genericFilers":[],"latestUpdates":[],"manufacturing":[],"crossReferences":{"UNII":"83B517YUVM","CHEBI":"CHEBI:135196","INN_ID":"5622","UMLSCUI":"C0628924","ChEMBL_ID":"CHEMBL2105255","PUBCHEM_CID":"71139","SECONDARY_CAS_RN":"29769-70-8","MESH_SUPPLEMENTAL_RECORD_UI":"C050429"},"formularyStatus":[],"_enricherVersion":"v2","developmentCodes":[],"ownershipHistory":[],"publicationCount":1,"therapeuticAreas":["Pain"],"biosimilarFilings":[],"recentPublications":[{"date":"1986 Sep","pmid":"3770157","title":"Milverine: in vitro and in vivo activity on the animal and human colon.","journal":"Il Farmaco; edizione pratica"}],"companionDiagnostics":[],"genericManufacturerList":[],"status":"active","companyName":"","companyId":"","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Fenpyramine, also known as Milverine, is a small molecule drug in the milverine class. Its target and exact mechanism of action are unknown, but it is believed to work by affecting the body's response to pain. Fenpyramine is not FDA-approved for any indications, and its commercial status, patent status, and availability of generic manufacturers are also unknown. As a result, there is limited information available on its safety profile and efficacy. Further research is needed to fully understand the properties and potential uses of Fenpyramine.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"partial","dataCompleteness":{"mechanism":true,"indications":false,"safety":false,"trials":false,"score":1}}