{"id":"microsurfaced-split-thickness-skin-graft","safety":{"commonSideEffects":[{"rate":null,"effect":"Graft failure or poor integration"},{"rate":null,"effect":"Infection at graft site"},{"rate":null,"effect":"Scarring or contracture"},{"rate":null,"effect":"Donor site complications"}]},"_chembl":null,"_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"This product takes a patient's own split thickness skin and applies microsurfacing technology to enhance the graft's integration and healing properties. The microsurfacing modifies the graft surface to improve cell adhesion, vascularization, and incorporation into the wound bed, promoting faster and more effective wound closure and tissue repair.","oneSentence":"A microsurfaced split thickness skin graft is a processed autologous skin tissue product that provides a scaffold for wound healing and tissue regeneration.","_ai_confidence":"low"},"_scrapedAt":"2026-03-27T23:55:14.305Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Acute and chronic wound coverage"},{"name":"Burn wounds"},{"name":"Traumatic wounds requiring skin grafting"}]},"trialDetails":[{"nctId":"NCT04589442","phase":"PHASE4","title":"Microsurfaced Grafts in Deep Burn Wounds","status":"RECRUITING","sponsor":"CellTherX","startDate":"2021-01-04","conditions":"Burns, Wound Heal","enrollment":20}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":0,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":[],"phase":"marketed","status":"active","brandName":"microsurfaced split thickness skin graft","genericName":"microsurfaced split thickness skin graft","companyName":"CellTherX","companyId":"celltherx","modality":"Biologic","firstApprovalDate":"","aiSummary":"Microsurfaced split thickness skin graft is a type of skin graft used to treat burns and wound healing. It has been studied in clinical trials, including a prospective, randomized study to evaluate its effectiveness in deep burn wounds.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}