{"id":"micronized-dhacm","safety":{"commonSideEffects":[{"rate":null,"effect":"Infection"},{"rate":null,"effect":"Allergic reaction"},{"rate":null,"effect":"Wound drainage"}]},"_chembl":{"chemblId":"CHEMBL440275","moleculeType":"Small molecule","molecularWeight":"404.50"},"_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"dHACM is a decellularized human placental tissue product that contains native growth factors, cytokines, and extracellular matrix proteins. When micronized and applied to wounds or tissue defects, it acts as a biologic dressing and regenerative scaffold, promoting angiogenesis, epithelialization, and tissue remodeling while providing anti-inflammatory and antimicrobial properties.","oneSentence":"Micronized dehydrated human amnion/chorion membrane (dHACM) provides a biologic scaffold that promotes tissue regeneration and wound healing through growth factors and extracellular matrix components.","_ai_confidence":"medium"},"_scrapedAt":"2026-03-28T00:49:57.136Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Diabetic foot ulcers"},{"name":"Chronic wounds"},{"name":"Surgical wounds"}]},"trialDetails":[{"nctId":"NCT05796765","phase":"PHASE2","title":"Phase 2B Micronized DHACM vs. Saline in the Treatment of Knee Osteoarthritis","status":"TERMINATED","sponsor":"MiMedx Group, Inc.","startDate":"2023-03-24","conditions":"Knee Osteoarthritis","enrollment":43},{"nctId":"NCT03485157","phase":"PHASE2","title":"Micronized dHACM vs. Saline in the Treatment of Osteoarthritis of the Knee","status":"COMPLETED","sponsor":"MiMedx Group, Inc.","startDate":"2018-03-27","conditions":"Knee Osteoarthritis","enrollment":447},{"nctId":"NCT03414268","phase":"PHASE3","title":"Micronized dHACM Injectable for the Treatment of Plantar Fasciitis","status":"COMPLETED","sponsor":"MiMedx Group, Inc.","startDate":"2018-01-08","conditions":"Fasciitis, Plantar","enrollment":208},{"nctId":"NCT03414255","phase":"PHASE3","title":"Micronized dHACM Injectable for the Treatment of Achille Tendonitis","status":"COMPLETED","sponsor":"MiMedx Group, Inc.","startDate":"2018-01-09","conditions":"Tendonitis;Achilles","enrollment":146},{"nctId":"NCT02427191","phase":"PHASE2, PHASE3","title":"Micronized dHACM Injectable for the Treatment of Plantar Fasciitis","status":"COMPLETED","sponsor":"MiMedx Group, Inc.","startDate":"2015-03-31","conditions":"Fasciitis, Plantar","enrollment":147},{"nctId":"NCT01921569","phase":"NA","title":"Micronized Dehydrated Human Amniotic Membrane Suspension in the Treatment of Lateral Epicondylitis","status":"TERMINATED","sponsor":"MiMedx Group, Inc.","startDate":"2013-06","conditions":"Epicondylitis, Lateral Humeral","enrollment":5}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":5,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":["dHACM"],"phase":"phase_3","status":"active","brandName":"Micronized dHACM","genericName":"Micronized dHACM","companyName":"MiMedx Group, Inc.","companyId":"mimedx-group-inc","modality":"Biologic","firstApprovalDate":"","aiSummary":"Micronized dehydrated human amnion/chorion membrane (dHACM) provides a biologic scaffold that promotes tissue regeneration and wound healing through growth factors and extracellular matrix components. Used for Diabetic foot ulcers, Chronic wounds, Surgical wounds.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":2,"withResults":1},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}