{"id":"metralindole","rwe":[{"pmid":"37075433","year":"2023","title":"Molecular docking, ADMET and molecular dynamics simulation revealed metralindole as a multitargeted inhibitor for division kinases.","finding":"","journal":"Brazilian journal of biology = Revista brasleira de biologia","studyType":"Clinical Study"},{"pmid":"9804284","year":"1998","title":"Clozapine and several other antipsychotic/antidepressant drugs preferentially block the same 'core' fraction of GABA(A) receptors.","finding":"","journal":"Neurochemical research","studyType":"Clinical Study"}],"tags":[{"label":"Small Molecule","category":"modality"},{"label":"Active","category":"status"}],"phase":"phase_2","safety":{},"trials":[],"aliases":[],"patents":[],"pricing":[],"allNames":["metralindole","metralindole hydrochloride","metralindole HCl"],"offLabel":[],"synonyms":["metralindole","metralindole hydrochloride","metralindole HCl"],"timeline":[],"approvals":[],"ecosystem":[],"mechanism":{"modality":"Small Molecule","explanation":"Imagine your body's cells are like locks, and METRALINDOLE is a key that fits into those locks. When it binds to its target, it can either turn the lock on or off, depending on the desired effect. This can help regulate various cellular processes and potentially treat different diseases.","oneSentence":"METRALINDOLE is a small molecule that interacts with specific biological pathways to produce its effects.","technicalDetail":"METRALINDOLE's mechanism of action is not well understood, but it is likely to involve binding to a specific protein or receptor, which triggers a cascade of downstream effects that ultimately lead to its therapeutic or adverse effects."},"commercial":{},"references":[{"id":1,"url":"https://drugcentral.org/drugcard/3358","fields":["approvals","synonyms","ATC","PK","indications","contraindications","DDIs","targets","patents","FAERS"],"source":"DrugCentral"},{"id":2,"url":"https://pubmed.ncbi.nlm.nih.gov/?term=METRALINDOLE","fields":["publications"],"source":"PubMed/NCBI"}],"_enrichedAt":"2026-03-30T12:42:35.706060","biosimilars":[],"competitors":[],"genericName":"metralindole","indications":{"approved":[],"offLabel":[],"pipeline":[]},"drugCategory":"active","labelChanges":[],"relatedDrugs":[],"trialDetails":[],"genericFilers":[],"latestUpdates":[],"manufacturing":[],"crossReferences":{"UNII":"2QW3FL6OPA","CHEBI":"CHEBI:135044","INN_ID":"4715","UMLSCUI":"C0066473","ChEMBL_ID":"CHEMBL1619017","DRUGBANK_ID":"DB09306","PUBCHEM_CID":"68713","SECONDARY_CAS_RN":"53734-79-5","MESH_SUPPLEMENTAL_RECORD_UI":"C027473"},"formularyStatus":[],"_enricherVersion":"v2","developmentCodes":[],"ownershipHistory":[],"publicationCount":2,"therapeuticAreas":["Other"],"biosimilarFilings":[],"recentPublications":[{"date":"2023","pmid":"37075433","title":"Molecular docking, ADMET and molecular dynamics simulation revealed metralindole as a multitargeted inhibitor for division kinases.","journal":"Brazilian journal of biology = Revista brasleira de biologia"},{"date":"1998 Oct","pmid":"9804284","title":"Clozapine and several other antipsychotic/antidepressant drugs preferentially block the same 'core' fraction of GABA(A) receptors.","journal":"Neurochemical research"}],"companionDiagnostics":[],"genericManufacturerList":[],"status":"active","brandName":"METRALINDOLE","companyName":"","companyId":"","modality":"Small molecule","firstApprovalDate":"","aiSummary":"METRALINDOLE is a small molecule. It is also known by the synonyms METRALINDOL and METRALINDOLE.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"partial","dataCompleteness":{"mechanism":true,"indications":false,"safety":false,"trials":false,"score":1}}