{"id":"meticel-ofteno","safety":{"commonSideEffects":[{"rate":null,"effect":"Transient blurred vision"},{"rate":null,"effect":"Eye irritation"},{"rate":null,"effect":"Mild ocular discomfort"}]},"_chembl":null,"_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"Methylcellulose is a cellulose derivative that functions as an artificial tear and ocular lubricant. It increases tear film viscosity and provides a protective coating over the cornea and conjunctiva, reducing friction and irritation. This helps relieve symptoms of dry eye and provides comfort during and after ophthalmic procedures.","oneSentence":"Meticel Ofteno is a topical ophthalmic preparation containing methylcellulose that lubricates and protects the ocular surface.","_ai_confidence":"medium"},"_scrapedAt":"2026-03-27T23:54:56.786Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Dry eye syndrome"},{"name":"Ocular irritation and discomfort"},{"name":"Lubricant for ophthalmic procedures"}]},"trialDetails":[{"nctId":"NCT06859476","phase":"PHASE4","title":"Evaluation of Manzanilla® and Meticel Ofteno® 0.5% for Providing a Relief Sensation to the Eyes","status":"COMPLETED","sponsor":"Laboratorios Sophia S.A de C.V.","startDate":"2025-05-23","conditions":"Ophthalmological Agent Toxicity","enrollment":168},{"nctId":"NCT06373653","phase":"PHASE4","title":"Study of Non-inferiority Between Manzanilla Sophia® and Meticel Ofteno® 0.5% for Providing a Soothing Sensation to the Eyes.","status":"WITHDRAWN","sponsor":"Laboratorios Sophia S.A de C.V.","startDate":"2025-02-11","conditions":"Eye Strain, Eye Strain of Both Eyes","enrollment":""}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":3,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":[],"phase":"marketed","status":"active","brandName":"Meticel Ofteno®","genericName":"Meticel Ofteno®","companyName":"Laboratorios Sophia S.A de C.V.","companyId":"laboratorios-sophia-s-a-de-c-v","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Meticel Ofteno is a topical ophthalmic preparation containing methylcellulose that acts as a lubricating and protective agent for the ocular surface. Used for Dry eye syndrome / Keratoconjunctivitis sicca, Ocular surface protection and lubrication.","enrichmentLevel":3,"visitCount":1,"trialStats":{"total":1,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}