{"id":"methylrosaniline","rwe":[{"pmid":"41363233","year":"2025","title":"[Christmas article: The dermatologist's Christmas palette - an experimental study of Christmas decorations with topical preparations].","finding":"","journal":"Ugeskrift for laeger","studyType":"Clinical Study"},{"pmid":"30000929","year":"2006","title":"Gentian Violet.","finding":"","journal":"","studyType":"Clinical Study"},{"pmid":"32154236","year":"2020","title":"Two-Dimensional Cellular and Three-Dimensional Bio-Printed Skin Models to Screen Topical-Use Compounds for Irritation Potential.","finding":"","journal":"Frontiers in bioengineering and biotechnology","studyType":"Clinical Study"},{"pmid":"29253305","year":"2017","title":"A Case of Serious Eye Injury Caused by a Mistaken Injection of Methylrosaniline Chloride During Vitreous Surgery.","finding":"","journal":"Ophthalmic surgery, lasers & imaging retina","studyType":"Clinical Study"},{"pmid":"22198115","year":"2011","title":"Higher magnification microsurgical repair of donor artery dissection in superficial temporal artery to middle cerebral artery anastomosis--technical note.","finding":"","journal":"Neurologia medico-chirurgica","studyType":"Clinical Study"}],"tags":[{"label":"methylrosaniline","category":"class"},{"label":"Small Molecule","category":"modality"},{"label":"D01AE02","category":"atc"},{"label":"Active","category":"status"}],"phase":"unknown","safety":{},"trials":["NCT03748667"],"aliases":[],"patents":[],"pricing":[],"allNames":"crystal violet base","offLabel":[],"synonyms":["methylrosaniline","Crystal Violet carbinol","Crystal Violet base"],"timeline":[],"approvals":[],"brandName":"Crystal Violet Base","ecosystem":[],"mechanism":{"modality":"Small Molecule","drugClass":"methylrosaniline","explanation":"Imagine your cells are like a city, and the proteins inside them are like the buildings. Crystal Violet Base is like a key that fits into a specific lock on one of those buildings, changing how it works and affecting the city's overall function. This can help to treat certain diseases, but it can also have unintended consequences if not used carefully.","oneSentence":"Crystal Violet Base works by binding to and altering the function of specific cellular targets.","technicalDetail":"Crystal Violet Base is a small molecule that interacts with cellular targets through non-covalent binding, altering their function and leading to downstream effects on cellular processes."},"commercial":{},"references":[{"id":1,"url":"https://drugcentral.org/drugcard/4670","fields":["approvals","synonyms","ATC","PK","indications","contraindications","DDIs","targets","patents","FAERS"],"source":"DrugCentral"},{"id":2,"url":"https://pubmed.ncbi.nlm.nih.gov/?term=methylrosaniline","fields":["publications"],"source":"PubMed/NCBI"}],"_enrichedAt":"2026-03-30T12:40:19.822819","biosimilars":[],"competitors":[{"drugName":"undecylenic acid","drugSlug":"undecylenic-acid","fdaApproval":"","relationship":"same-class"},{"drugName":"chlorphenesin carbamate","drugSlug":"chlorphenesin-carbamate","fdaApproval":"1965-06-14","patentStatus":"Unknown","relationship":"same-class"},{"drugName":"haloprogin","drugSlug":"haloprogin","fdaApproval":"","patentStatus":"Unknown","relationship":"same-class"},{"drugName":"selenium sulfide","drugSlug":"selenium-sulfide","fdaApproval":"1951-05-17","genericCount":6,"patentStatus":"Off-patent — generic available","relationship":"same-class"},{"drugName":"ciclopirox","drugSlug":"ciclopirox","fdaApproval":"1982-12-30","genericCount":17,"patentStatus":"Off-patent — generic available","relationship":"same-class"},{"drugName":"terbinafine","drugSlug":"terbinafine","fdaApproval":"1992-12-30","patentStatus":"Unknown","relationship":"same-class"},{"drugName":"tolnaftate","drugSlug":"tolnaftate","fdaApproval":"","relationship":"same-class"},{"drugName":"flucytosine","drugSlug":"flucytosine","fdaApproval":"1971-11-26","genericCount":6,"patentStatus":"Off-patent — generic 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sulfide","genericName":"selenium sulfide","approvalYear":"1951","relationship":"same-class"},{"drugId":"ciclopirox","brandName":"ciclopirox","genericName":"ciclopirox","approvalYear":"1982","relationship":"same-class"},{"drugId":"terbinafine","brandName":"terbinafine","genericName":"terbinafine","approvalYear":"1992","relationship":"same-class"},{"drugId":"tolnaftate","brandName":"tolnaftate","genericName":"tolnaftate","approvalYear":"","relationship":"same-class"},{"drugId":"flucytosine","brandName":"flucytosine","genericName":"flucytosine","approvalYear":"1971","relationship":"same-class"},{"drugId":"naftifine","brandName":"naftifine","genericName":"naftifine","approvalYear":"1988","relationship":"same-class"},{"drugId":"butenafine","brandName":"butenafine","genericName":"butenafine","approvalYear":"1996","relationship":"same-class"}],"trialDetails":[{"nctId":"NCT03748667","phase":"N/A","title":"Diagnostic Accuracy of Deep Submucosal Invasion: White Light Endoscopy vs Invasive Pattern Based on NBI/BLI ± Chromoendoscopy","status":"COMPLETED","sponsor":"Althaia Xarxa Assistencial Universitària de Manresa","isPivotal":false,"enrollment":426,"indication":"Colorectal Cancer, Colorectal Polyp","completionDate":"2022-10-30"}],"genericFilers":[],"latestUpdates":[],"manufacturing":[],"administration":{},"crossReferences":{"CHEBI":"CHEBI:136016","UMLSCUI":"C0301302","ChEMBL_ID":"CHEMBL592105","DRUGBANK_ID":"DB00406","PUBCHEM_CID":"68050","SNOMEDCT_US":"61306004"},"formularyStatus":[],"_enricherVersion":"v2","developmentCodes":[],"ownershipHistory":[],"publicationCount":19,"therapeuticAreas":["Other"],"atcClassification":{"source":"DrugCentral","atcCode":"D01AE02","allCodes":["D01AE02","G01AX09"]},"biosimilarFilings":[],"recentPublications":[{"date":"2025 Dec 8","pmid":"41363233","title":"[Christmas article: The dermatologist's Christmas palette - an experimental study of Christmas decorations with topical preparations].","journal":"Ugeskrift for 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methylrosaniline, is a small molecule drug of the methylrosaniline class. Unfortunately, there is limited information available on this compound, and it is not clear what it is used to treat or its current commercial status. As a result, it is difficult to provide a comprehensive summary of its use, safety, and efficacy. Further research is needed to determine the potential benefits and risks of this compound. It is not currently listed as an approved medication by the FDA.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"partial","dataCompleteness":{"mechanism":true,"indications":false,"safety":false,"trials":true,"score":2}}