{"id":"methylprednisolone-suleptanate","rwe":[],"tags":[{"label":"Corticosteroid","category":"class"},{"label":"Small Molecule","category":"modality"},{"label":"Active","category":"status"},{"label":"Anti-Inflammatory Agents","category":"pharmacology"},{"label":"Antiemetics","category":"pharmacology"},{"label":"Central Nervous System Agents","category":"pharmacology"},{"label":"Gastrointestinal Agents","category":"pharmacology"},{"label":"Glucocorticoids","category":"pharmacology"},{"label":"Hormones","category":"pharmacology"},{"label":"Neuroprotective Agents","category":"pharmacology"},{"label":"Peripheral Nervous System Agents","category":"pharmacology"},{"label":"Protective Agents","category":"pharmacology"}],"phase":"phase_2","safety":{},"trials":[],"aliases":[],"patents":[],"pricing":[],"allNames":["methylprednisolone suleptanate","methylprednisolone suleptanate sodium salt","methylprednisolone suleptanate sodium"],"offLabel":[],"synonyms":["methylprednisolone suleptanate","methylprednisolone suleptanate sodium salt","methylprednisolone suleptanate sodium"],"timeline":[],"approvals":[],"ecosystem":[],"mechanism":{"moaClass":"Corticosteroid Hormone Receptor Agonists","modality":"Small Molecule","drugClass":"Corticosteroid","explanation":"Imagine your immune system is like a fire that gets out of control. Corticosteroids like methylprednisolone suleptanate are like fire extinguishers that help put out the flames by reducing the production of chemicals that cause inflammation. This helps to calm down the immune response and reduce swelling and pain.","oneSentence":"Methylprednisolone suleptanate works by binding to glucocorticoid receptors, which then suppress the expression of pro-inflammatory genes.","technicalDetail":"Methylprednisolone suleptanate exerts its effects by binding to glucocorticoid receptors, which then translocate to the nucleus and bind to specific DNA sequences, leading to the suppression of pro-inflammatory gene expression and the induction of anti-inflammatory genes."},"commercial":{},"references":[{"id":1,"url":"https://drugcentral.org/drugcard/1772","fields":["approvals","synonyms","ATC","PK","indications","contraindications","DDIs","targets","patents","FAERS"],"source":"DrugCentral"},{"id":2,"url":"https://pubmed.ncbi.nlm.nih.gov/?term=METHYLPREDNISOLONE SULEPTANATE","fields":["publications"],"source":"PubMed/NCBI"}],"_enrichedAt":"2026-03-30T14:26:23.176803","biosimilars":[],"competitors":[],"genericName":"methylprednisolone suleptanate","indications":{"approved":[],"offLabel":[],"pipeline":[]},"drugCategory":"active","labelChanges":[],"relatedDrugs":[],"trialDetails":[],"genericFilers":[],"latestUpdates":[],"manufacturing":[],"crossReferences":{"MMSL":"1041","NDDF":"002160","UNII":"G6CS53NCVS","CHEBI":"CHEBI:135864","VANDF":"4018068","INN_ID":"5945","RXNORM":"6902","UMLSCUI":"C0066429","ChEMBL_ID":"CHEMBL2106453","KEGG_DRUG":"D05002","DRUGBANK_ID":"DB00959","PUBCHEM_CID":"23663977","SNOMEDCT_US":"116593003","MESH_DESCRIPTOR_UI":"D008775","MESH_SUPPLEMENTAL_RECORD_UI":"C052305"},"formularyStatus":[],"_enricherVersion":"v2","developmentCodes":[],"ownershipHistory":[],"publicationCount":11,"therapeuticAreas":["Immunology"],"biosimilarFilings":[],"recentPublications":[],"companionDiagnostics":[],"genericManufacturerList":[],"status":"active","brandName":"METHYLPREDNISOLONE SULEPTANATE","companyName":"","companyId":"","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Methylprednisolone suleptanate is a small molecule medication. It is also known by other names, including Medrol, Promedrol, and PNU-67590A.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"partial","dataCompleteness":{"mechanism":true,"indications":false,"safety":false,"trials":false,"score":1}}