{"id":"methylparaben","rwe":[],"tags":[{"label":"Standardized Chemical Allergen","category":"class"},{"label":"Small Molecule","category":"modality"},{"label":"Carbonic anhydrase 7","category":"target"},{"label":"CA7","category":"gene"},{"label":"CA12","category":"gene"},{"label":"CA1","category":"gene"},{"label":"Topical","category":"route"},{"label":"Concentrate","category":"form"},{"label":"Cream","category":"form"},{"label":"Gel","category":"form"},{"label":"Liquid","category":"form"},{"label":"Active","category":"status"},{"label":"Pharmaceutic Aids","category":"pharmacology"},{"label":"Preservatives, Pharmaceutical","category":"pharmacology"}],"phase":"unknown","safety":{},"trials":[],"aliases":[],"patents":[],"pricing":[],"allNames":"maseptol","offLabel":[],"synonyms":["methyl parahydroxybenzoate","methylparaben","maseptol","p-carbomethoxyphenol","p-hydroxybenzoic acid methyl ester","p-methoxycarbonylphenol"],"timeline":[],"approvals":[],"brandName":"Maseptol","ecosystem":[],"mechanism":{"target":"Carbonic anhydrase 1, Carbonic anhydrase 12, Carbonic anhydrase 14","targets":[{"gene":"CA7","source":"DrugCentral","target":"Carbonic anhydrase 7","protein":"Carbonic anhydrase 7"},{"gene":"CA12","source":"DrugCentral","target":"Carbonic anhydrase 12","protein":"Carbonic anhydrase 12"},{"gene":"CA1","source":"DrugCentral","target":"Carbonic anhydrase 1","protein":"Carbonic anhydrase 1"},{"gene":"CA2","source":"DrugCentral","target":"Carbonic anhydrase 2","protein":"Carbonic anhydrase 2"},{"gene":"CA14","source":"DrugCentral","target":"Carbonic anhydrase 14","protein":"Carbonic anhydrase 14"},{"gene":"CA9","source":"DrugCentral","target":"Carbonic anhydrase 9","protein":"Carbonic anhydrase 9"}],"modality":"Small Molecule","drugClass":"Standardized Chemical Allergen","explanation":"Think of it like a key fitting into a lock. Maseptol is the key, and carbonic anhydrase 7 is the lock. When they bind together, it can affect how the protein works, which may help diagnose or treat allergic reactions.","oneSentence":"Maseptol works by binding to carbonic anhydrase 7, a protein involved in various cellular processes.","technicalDetail":"Maseptol's binding to carbonic anhydrase 7 may alter the enzyme's activity, leading to changes in cellular metabolism and potentially triggering an allergic response."},"_wikipedia":{"url":"https://en.wikipedia.org/wiki/Methylparaben","title":"Methylparaben","extract":"Methylparaben one of the parabens, is a preservative with the chemical formula CH3O2CC6H4OH. It is the methyl ester of p-hydroxybenzoic acid. Several related esters are known. Together they are the most common preservatives in cosmetics and foods. Among their advantages, parabens are inexpensive, colorless, stable, odorless, and readily biodegraded."},"commercial":{},"references":[{"id":1,"url":"https://drugcentral.org/drugcard/1766","fields":["approvals","synonyms","ATC","PK","indications","contraindications","DDIs","targets","patents","FAERS"],"source":"DrugCentral"},{"id":2,"url":"https://clinicaltrials.gov/search?intr=methylparaben","fields":["trials"],"source":"ClinicalTrials.gov"},{"id":3,"url":"https://pubmed.ncbi.nlm.nih.gov/?term=methylparaben","fields":["publications"],"source":"PubMed/NCBI"},{"id":4,"url":"https://en.wikipedia.org/wiki/Methylparaben","fields":["history","overview"],"source":"Wikipedia"}],"_enrichedAt":"2026-03-30T14:23:41.388889","biosimilars":[],"competitors":[{"drugName":"acetazolamide","drugSlug":"acetazolamide","fdaApproval":"1953-07-27","genericCount":29,"patentStatus":"Off-patent — generic available","relationship":"same-target"},{"drugName":"acetohydroxamic 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It targets carbonic anhydrase 7, but its exact mechanism of action is unclear. Maseptol's commercial status and approved indications are unknown. As a standardized chemical allergen, it may be used to diagnose or treat allergic reactions. However, its safety profile and pharmacokinetic properties are not well established.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"partial","dataCompleteness":{"mechanism":true,"indications":false,"safety":false,"trials":true,"score":2}}