{"id":"methoserpidine","rwe":[{"pmid":"4382539","year":"1967","title":"The effects of methoserpidine and cyclopenthiazide upon elevated arterial pressure.","finding":"","journal":"The Journal of the College of General Practitioners","studyType":"Clinical Study"},{"pmid":"5868793","year":"1965","title":"[A case of depression caused by methoserpidine].","finding":"","journal":"Lakartidningen","studyType":"Clinical Study"},{"pmid":"14337851","year":"1965","title":"DEPRESSION AFTER METHOSERPIDINE.","finding":"","journal":"Lancet (London, England)","studyType":"Clinical Study"},{"pmid":"14272419","year":"1964","title":"USE OF METHOSERPIDINE-BENZTHIAZIDE COMBINATION IN THE TREATMENT OF ESSENTIAL HYPERTENSION.","finding":"","journal":"The British journal of clinical practice","studyType":"Clinical Study"},{"pmid":"13935016","year":"1962","title":"[Clinical trials with a preparation potentiating the hypotensive action of methoserpidine].","finding":"","journal":"Lille medical : journal de la Faculte de medecine et de pharmacie de l'Universite de Lille","studyType":"Clinical Study"}],"tags":[{"label":"methoserpidine","category":"class"},{"label":"Small Molecule","category":"modality"},{"label":"C02AA06","category":"atc"},{"label":"Active","category":"status"}],"phase":"phase_2","safety":{},"trials":[],"aliases":[],"patents":[],"pricing":[],"allNames":"decaserpin","offLabel":[],"synonyms":["methoserpidine","10-Methoxydeserpidine","decaserpin","decaserpine","decaserpyl","decoserpyl"],"timeline":[],"approvals":[],"brandName":"Decaserpin","ecosystem":[],"mechanism":{"modality":"Small Molecule","drugClass":"methoserpidine","explanation":"Unfortunately, we don't know exactly how decaserpin works, but it's thought to affect the body's response to certain stimuli. This can lead to changes in how the body functions, but more research is needed to understand the details. Essentially, decaserpin is a mystery in terms of its mechanism of action.","oneSentence":"Decaserpin works by interacting with an unknown target to produce its effects.","technicalDetail":"Decaserpin's mechanism of action is currently unknown, and further research is needed to determine its pharmacological properties and potential therapeutic applications."},"commercial":{},"references":[{"id":1,"url":"https://drugcentral.org/drugcard/1750","fields":["approvals","synonyms","ATC","PK","indications","contraindications","DDIs","targets","patents","FAERS"],"source":"DrugCentral"},{"id":2,"url":"https://pubmed.ncbi.nlm.nih.gov/?term=METHOSERPIDINE","fields":["publications"],"source":"PubMed/NCBI"}],"_enrichedAt":"2026-03-30T15:02:11.704796","biosimilars":[],"competitors":[{"drugName":"rescinnamine","drugSlug":"rescinnamine","fdaApproval":"1956-10-31","genericCount":1,"patentStatus":"Off-patent — generic available","relationship":"same-class"},{"drugName":"reserpine","drugSlug":"reserpine","fdaApproval":"1955-10-12","genericCount":17,"patentStatus":"Off-patent — generic available","relationship":"same-class"},{"drugName":"deserpidine","drugSlug":"deserpidine","fdaApproval":"1957-04-19","patentStatus":"Unknown","relationship":"same-class"}],"genericName":"methoserpidine","indications":{"approved":[],"offLabel":[],"pipeline":[]},"drugCategory":"active","labelChanges":[],"relatedDrugs":[{"drugId":"rescinnamine","brandName":"rescinnamine","genericName":"rescinnamine","approvalYear":"1956","relationship":"same-class"},{"drugId":"reserpine","brandName":"reserpine","genericName":"reserpine","approvalYear":"1955","relationship":"same-class"},{"drugId":"deserpidine","brandName":"deserpidine","genericName":"deserpidine","approvalYear":"1957","relationship":"same-class"}],"trialDetails":[],"genericFilers":[],"latestUpdates":[],"manufacturing":[],"crossReferences":{"NDDF":"004005","UNII":"8F8C1JQH53","CHEBI":"CHEBI:135848","INN_ID":"1081","RXNORM":"235829","UMLSCUI":"C0771017","ChEMBL_ID":"CHEMBL3989541","KEGG_DRUG":"D07166","DRUGBANK_ID":"DB13631","PUBCHEM_CID":"71798"},"formularyStatus":[],"_enricherVersion":"v2","developmentCodes":[],"ownershipHistory":[],"publicationCount":9,"therapeuticAreas":["Other"],"atcClassification":{"source":"DrugCentral","atcCode":"C02AA06","allCodes":["C02AA06","C02LA04"]},"biosimilarFilings":[],"recentPublications":[{"date":"1967 Jan","pmid":"4382539","title":"The effects of methoserpidine and cyclopenthiazide upon elevated arterial pressure.","journal":"The Journal of the College of General Practitioners"},{"date":"1965 Sep 29","pmid":"5868793","title":"[A case of depression caused by methoserpidine].","journal":"Lakartidningen"},{"date":"1965 Sep 4","pmid":"14337851","title":"DEPRESSION AFTER METHOSERPIDINE.","journal":"Lancet (London, England)"},{"date":"1964 Apr","pmid":"14272419","title":"USE OF METHOSERPIDINE-BENZTHIAZIDE COMBINATION IN THE TREATMENT OF ESSENTIAL HYPERTENSION.","journal":"The British journal of clinical practice"},{"date":"1962 Aug-Sep","pmid":"13935016","title":"[Clinical trials with a preparation potentiating the hypotensive action of methoserpidine].","journal":"Lille medical : journal de la Faculte de medecine et de pharmacie de l'Universite de Lille"}],"companionDiagnostics":[],"genericManufacturerList":[],"status":"active","companyName":"","companyId":"","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Decaserpin is a small molecule with the synonyms 10-MD, (-)-10-METHOXYDESERPIDINE, 10-METHOXYDESERPIDINE, DEASERPYL, DECASERPIL, and DECASERPIN.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"partial","dataCompleteness":{"mechanism":true,"indications":false,"safety":false,"trials":false,"score":1}}