{"id":"methandriol","rwe":[{"pmid":"40675078","year":"2025","title":"Nanostructure-enhanced Raman spectroscopy for sensitive and on-site monitoring of anabolic-androgenic steroids in food and drug products.","finding":"","journal":"Food chemistry","studyType":"Clinical Study"},{"pmid":"39444551","year":"2024","title":"Amlexanox reduces new-onset atrial fibrillation risk in sepsis by downregulating S100A12: a Mendelian randomization study.","finding":"","journal":"Frontiers in cardiovascular medicine","studyType":"Clinical Study"},{"pmid":"39265962","year":"2024","title":"Viral reprogramming by nervous necrosis virus alters key metabolites and its pathways in sevenband grouper (Hyporthodus septemfasciatus) gills.","finding":"","journal":"Fish & shellfish immunology","studyType":"Clinical Study"},{"pmid":"25001892","year":"2014","title":"The Escherichia coli glucuronylsynthase promoted synthesis of steroid glucuronides: improved practicality and broader scope.","finding":"","journal":"Organic & biomolecular chemistry","studyType":"Clinical Study"},{"pmid":"23534422","year":"2013","title":"The metabolism of anabolic-androgenic steroids in the greyhound.","finding":"","journal":"Bioanalysis","studyType":"Clinical Study"}],"tags":[{"label":"methandriol","category":"class"},{"label":"Small Molecule","category":"modality"},{"label":"Active","category":"status"},{"label":"Anabolic Agents","category":"pharmacology"},{"label":"Hormones","category":"pharmacology"}],"phase":"phase_2","safety":{},"trials":[],"aliases":[],"patents":[],"pricing":[],"allNames":"androdiol","offLabel":[],"synonyms":["methandriol","androdiol","diolandrone","mestenediol","metandiol","metandriol","methanabol","methandrolan","methylandrostenediol","neosteron"],"timeline":[],"approvals":[],"brandName":"Androdiol","ecosystem":[],"mechanism":{"modality":"Small Molecule","drugClass":"methandriol","explanation":"Imagine your body has locks on the doors of cells that only male hormones can open. Android is a key that fits into these locks, allowing the hormone-like effects to flow into the cell and stimulate growth and development.","oneSentence":"Android works by binding to androgen receptors in the body, triggering a cascade of effects that mimic the action of male hormones.","technicalDetail":"Android (methandriol) is a 17α-methylated anabolic-androgenic steroid that undergoes reduction to form 17α-methyldihydrotestosterone, which then binds to androgen receptors to exert its effects."},"commercial":{},"references":[{"id":1,"url":"https://drugcentral.org/drugcard/1733","fields":["approvals","synonyms","ATC","PK","indications","contraindications","DDIs","targets","patents","FAERS"],"source":"DrugCentral"},{"id":2,"url":"https://pubmed.ncbi.nlm.nih.gov/?term=METHANDRIOL","fields":["publications"],"source":"PubMed/NCBI"}],"_enrichedAt":"2026-03-30T12:37:08.210559","biosimilars":[],"competitors":[],"genericName":"methandriol","indications":{"approved":[],"offLabel":[],"pipeline":[]},"drugCategory":"active","labelChanges":[],"relatedDrugs":[],"trialDetails":[],"genericFilers":[],"latestUpdates":[],"manufacturing":[],"crossReferences":{"NUI":"N0000147911","NDDF":"001256","UNII":"5730Z864KG","VUID":"4019822","CHEBI":"CHEBI:34834","VANDF":"4019822","INN_ID":"1882","RXNORM":"6817","UMLSCUI":"C0025615","ChEMBL_ID":"CHEMBL1079446","KEGG_DRUG":"D08196","PUBCHEM_CID":"229021","SNOMEDCT_US":"126127002","MESH_DESCRIPTOR_UI":"D008695"},"formularyStatus":[],"_enricherVersion":"v2","developmentCodes":[],"ownershipHistory":[],"publicationCount":16,"therapeuticAreas":["Other"],"biosimilarFilings":[],"recentPublications":[{"date":"2025 Nov 15","pmid":"40675078","title":"Nanostructure-enhanced Raman spectroscopy for sensitive and on-site monitoring of anabolic-androgenic steroids in food and drug products.","journal":"Food chemistry"},{"date":"2024","pmid":"39444551","title":"Amlexanox reduces new-onset atrial fibrillation risk in sepsis by downregulating S100A12: a Mendelian randomization study.","journal":"Frontiers in cardiovascular medicine"},{"date":"2024 Nov","pmid":"39265962","title":"Viral reprogramming by nervous necrosis virus alters key metabolites and its pathways in sevenband grouper (Hyporthodus septemfasciatus) gills.","journal":"Fish & shellfish immunology"},{"date":"2014 Aug 28","pmid":"25001892","title":"The Escherichia coli glucuronylsynthase promoted synthesis of steroid glucuronides: improved practicality and broader scope.","journal":"Organic & biomolecular chemistry"},{"date":"2013 Apr","pmid":"23534422","title":"The metabolism of anabolic-androgenic steroids in the greyhound.","journal":"Bioanalysis"}],"companionDiagnostics":[],"genericManufacturerList":[],"status":"active","companyName":"","companyId":"","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Android (Methandriol) is a synthetic anabolic-androgenic steroid of the methandriol class. It is a small molecule that works by mimicking the effects of male hormones in the body, such as testosterone. Android is used to treat conditions associated with low testosterone levels, but its exact target and approved indications are unknown. The commercial status of Android is unclear, and it may be off-patent or have a complex patent situation. As a result, its availability and safety considerations are uncertain.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"partial","dataCompleteness":{"mechanism":true,"indications":false,"safety":false,"trials":false,"score":1}}