{"id":"metabutoxycaine","rwe":[],"tags":[{"label":"metabutoxycaine","category":"class"},{"label":"Small Molecule","category":"modality"},{"label":"Active","category":"status"}],"phase":"unknown","safety":{},"trials":[],"aliases":[],"patents":[],"pricing":[],"allNames":"primacaine","offLabel":[],"synonyms":["primacaine","metabutoxycaine hydrochloride","metabutoxycaine HCl","metabutoxycaine"],"timeline":[],"approvals":[],"brandName":"Primacaine","ecosystem":[],"mechanism":{"modality":"Small Molecule","drugClass":"metabutoxycaine","explanation":"Imagine your nerve cells are like a busy highway where signals are constantly being sent and received. Primacaine is like a roadblock that prevents pain signals from getting through, providing relief from pain. This is achieved by blocking the flow of sodium ions into the nerve cells, which is essential for the transmission of pain signals.","oneSentence":"Primacaine works by blocking sodium channels in nerve cells to prevent the transmission of pain signals.","technicalDetail":"Primacaine exerts its analgesic effects by selectively blocking voltage-gated sodium channels, specifically the Nav1.7 subtype, which is involved in the transmission of pain signals."},"commercial":{},"references":[{"id":1,"url":"https://drugcentral.org/drugcard/3771","fields":["approvals","synonyms","ATC","PK","indications","contraindications","DDIs","targets","patents","FAERS"],"source":"DrugCentral"},{"id":2,"url":"https://pubmed.ncbi.nlm.nih.gov/?term=metabutoxycaine","fields":["publications"],"source":"PubMed/NCBI"}],"_enrichedAt":"2026-03-30T12:36:21.993771","biosimilars":[],"competitors":[],"genericName":"metabutoxycaine","indications":{"approved":[],"offLabel":[],"pipeline":[]},"drugCategory":"active","labelChanges":[],"relatedDrugs":[],"trialDetails":[],"genericFilers":[],"latestUpdates":[],"manufacturing":[],"crossReferences":{"UNII":"AMV9L2WT8K","CHEBI":"CHEBI:135313","UMLSCUI":"C0301290","ChEMBL_ID":"CHEMBL2110975","PUBCHEM_CID":"19247","SNOMEDCT_US":"51260007","SECONDARY_CAS_RN":"550-01-6","MESH_SUPPLEMENTAL_RECORD_UI":"C484910"},"formularyStatus":[],"_enricherVersion":"v2","developmentCodes":[],"ownershipHistory":[],"publicationCount":1,"therapeuticAreas":["Pain"],"biosimilarFilings":[],"recentPublications":[],"companionDiagnostics":[],"genericManufacturerList":[],"status":"active","companyName":"","companyId":"unknown","modality":"Small Molecule","firstApprovalDate":"","aiSummary":"Primacaine, also known as metabutoxycaine, is a local anesthetic used in dentistry. It is a small molecule with the U.S. patent number 2,882,296.","enrichmentLevel":3,"visitCount":1,"trialStats":{"total":0,"withResults":0},"verificationStatus":"partial","dataCompleteness":{"mechanism":true,"indications":false,"safety":false,"trials":false,"score":1}}