{"id":"mescaline-sodium-enteric-coated-tablets","safety":{"commonSideEffects":[{"rate":null,"effect":"Hallucinations or altered perception"},{"rate":null,"effect":"Nausea or gastrointestinal distress"},{"rate":null,"effect":"Anxiety or psychological distress"},{"rate":null,"effect":"Elevated blood pressure or heart rate"}]},"_chembl":null,"_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"Mescaline binds to and activates serotonin receptors, particularly the 5-HT2A subtype, which modulates perception, mood, and cognition. The enteric coating allows delayed release in the small intestine to improve tolerability and absorption. This mechanism underlies its psychoactive and potential therapeutic effects on mood and perception-related disorders.","oneSentence":"Mescaline is a naturally occurring psychedelic alkaloid that acts as a non-selective serotonin receptor agonist, primarily at 5-HT2A receptors.","_ai_confidence":"low"},"_scrapedAt":"2026-03-27T23:34:24.672Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Depression or mood disorders (investigational/research use)"},{"name":"Potential use in psychiatric conditions (specific approved indications unclear)"}]},"trialDetails":[{"nctId":"NCT05933213","phase":"PHASE4","title":"Comparing Mescaline Sodium Enteric-coated Tablets vs Morte-mescaline in the Treatment of Adult Lupus Nephritis","status":"UNKNOWN","sponsor":"Xiangya Hospital of Central South University","startDate":"2023-07-06","conditions":"Lupus Nephritis","enrollment":205}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":0,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":[],"phase":"marketed","status":"active","brandName":"Mescaline sodium enteric-coated tablets","genericName":"Mescaline sodium enteric-coated tablets","companyName":"Xiangya Hospital of Central South University","companyId":"xiangya-hospital-of-central-south-university","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Mescaline sodium enteric-coated tablets are being studied as a potential treatment for adult lupus nephritis in a clinical trial. Mescaline is a small molecule with the chemical name 2-(3,4,5-Trimethoxyphenyl)Ethanamine.","enrichmentLevel":3,"visitCount":1,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}