{"id":"mepiprazole","rwe":[{"pmid":"31661620","year":"2019","title":"Regioselective Synthesis of Functionalized 3- or 5-Fluoroalkyl Isoxazoles and Pyrazoles from Fluoroalkyl Ynones and Binucleophiles.","finding":"","journal":"The Journal of organic chemistry","studyType":"Clinical Study"},{"pmid":"24847516","year":"2014","title":"Development of LC-MS/MS method for the determination of dapiprazole on dried blood spots and urine: application to pharmacokinetics.","finding":"","journal":"Biomedical chromatography : BMC","studyType":"Clinical Study"},{"pmid":"6311738","year":"1983","title":"Evidence that blood pressure reduction by serotonin antagonists is related to alpha receptor blockade in spontaneously hypertensive rats.","finding":"","journal":"Hypertension (Dallas, Tex. : 1979)","studyType":"Clinical Study"},{"pmid":"6128394","year":"1982","title":"1-m-Chlorophenylpiperazine is an active metabolite common to the psychotropic drugs trazodone, etoperidone and mepiprazole.","finding":"","journal":"The Journal of pharmacy and pharmacology","studyType":"Clinical Study"},{"pmid":"7255266","year":"1980","title":"Central action of mepiprazole.","finding":"","journal":"Polish journal of pharmacology and pharmacy","studyType":"Clinical Study"}],"tags":[{"label":"Small Molecule","category":"modality"},{"label":"Active","category":"status"}],"phase":"phase_2","safety":{},"trials":[],"aliases":[],"patents":[],"pricing":[],"allNames":"psigodal","offLabel":[],"synonyms":["mepiprazole","mepiprazole hydrochloride","psigodal","mepiprazole dihydrochloride"],"timeline":[],"approvals":[],"brandName":"Psigodal","ecosystem":[],"mechanism":{"modality":"Small Molecule","explanation":"Imagine your brain is a busy city with many different streets and intersections. Mepiprazole helps to regulate the flow of traffic by adjusting the signals that control the movement of neurotransmitters, which are like the cars on the road. This can help to improve communication between different parts of the brain and alleviate symptoms of certain conditions.","oneSentence":"Mepiprazole is thought to work by modulating neurotransmitter activity in the brain.","technicalDetail":"Mepiprazole is a small molecule that acts as a partial agonist at serotonin receptors, potentially influencing mood regulation and other cognitive processes."},"commercial":{},"references":[{"id":1,"url":"https://drugcentral.org/drugcard/5097","fields":["approvals","synonyms","ATC","PK","indications","contraindications","DDIs","targets","patents","FAERS"],"source":"DrugCentral"},{"id":2,"url":"https://pubmed.ncbi.nlm.nih.gov/?term=MEPIPRAZOLE","fields":["publications"],"source":"PubMed/NCBI"}],"_enrichedAt":"2026-03-30T14:19:13.491509","biosimilars":[],"competitors":[],"genericName":"mepiprazole","indications":{"approved":[],"offLabel":[],"pipeline":[]},"drugCategory":"active","labelChanges":[],"relatedDrugs":[],"trialDetails":[],"genericFilers":[],"latestUpdates":[],"manufacturing":[],"crossReferences":{"UNII":"977BAL0NR7","CHEBI":"CHEBI:134701","INN_ID":"2954","UMLSCUI":"C0065963","ChEMBL_ID":"CHEMBL2106537","DRUGBANK_ID":"DB09197","PUBCHEM_CID":"71897","SECONDARY_CAS_RN":"20344-15-4","MESH_SUPPLEMENTAL_RECORD_UI":"C008351"},"formularyStatus":[],"_enricherVersion":"v2","developmentCodes":[],"ownershipHistory":[],"publicationCount":12,"therapeuticAreas":["Neuroscience"],"biosimilarFilings":[],"recentPublications":[{"date":"2019 Dec 6","pmid":"31661620","title":"Regioselective Synthesis of Functionalized 3- or 5-Fluoroalkyl Isoxazoles and Pyrazoles from Fluoroalkyl Ynones and Binucleophiles.","journal":"The Journal of organic chemistry"},{"date":"2014 May","pmid":"24847516","title":"Development of LC-MS/MS method for the determination of dapiprazole on dried blood spots and urine: application to pharmacokinetics.","journal":"Biomedical chromatography : BMC"},{"date":"1983 Sep-Oct","pmid":"6311738","title":"Evidence that blood pressure reduction by serotonin antagonists is related to alpha receptor blockade in spontaneously hypertensive rats.","journal":"Hypertension (Dallas, Tex. : 1979)"},{"date":"1982 Oct","pmid":"6128394","title":"1-m-Chlorophenylpiperazine is an active metabolite common to the psychotropic drugs trazodone, etoperidone and mepiprazole.","journal":"The Journal of pharmacy and pharmacology"},{"date":"1980 Jul-Aug","pmid":"7255266","title":"Central action of mepiprazole.","journal":"Polish journal of pharmacology and pharmacy"}],"companionDiagnostics":[],"genericManufacturerList":[],"status":"active","companyName":"","companyId":"","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Mepiprazole, also known as Psigodal, is a small molecule drug with unknown target and drug class. It is currently owned by an unspecified company, and its commercial status is unclear. Mepiprazole is used to treat unspecified indications, but its FDA approval status is unknown. The drug's pharmacokinetic properties, including half-life and bioavailability, are also unknown. Further research is needed to fully understand the safety and efficacy of mepiprazole.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"partial","dataCompleteness":{"mechanism":true,"indications":false,"safety":false,"trials":false,"score":1}}