{"id":"mepiperphenidol","rwe":[{"pmid":"11502595","year":"2001","title":"Interaction of cations, anions, and weak base quinine with rat renal cation transporter rOCT2 compared with rOCT1.","finding":"","journal":"American journal of physiology. Renal physiology","studyType":"Clinical Study"},{"pmid":"11123374","year":"2001","title":"A novel zidovudine uptake system in microglia.","finding":"","journal":"The Journal of pharmacology and experimental therapeutics","studyType":"Clinical Study"},{"pmid":"9864277","year":"1998","title":"Substrate specificity of organic cation/H+ exchange in avian renal brush-border membranes.","finding":"","journal":"The Journal of pharmacology and experimental therapeutics","studyType":"Clinical Study"},{"pmid":"9262381","year":"1997","title":"Functional characterization of choroid plexus epithelial cells in primary culture.","finding":"","journal":"The Journal of pharmacology and experimental therapeutics","studyType":"Clinical Study"},{"pmid":"9034623","year":"1996","title":"Precision-cut dog renal cortical slices in dynamic organ culture for the study of cisplatin nephrotoxicity.","finding":"","journal":"Cell biology and toxicology","studyType":"Clinical Study"}],"tags":[{"label":"Small Molecule","category":"modality"},{"label":"Active","category":"status"}],"phase":"unknown","safety":{},"trials":[],"aliases":[],"patents":[],"pricing":[],"allNames":"piperphenamine","offLabel":[],"synonyms":["mepiperphenidol","mepiperphenidol bromide","mepiperphenidyl","piperphenamine"],"timeline":[],"approvals":[],"brandName":"Piperphenamine","ecosystem":[],"mechanism":{"modality":"Small Molecule","explanation":"Imagine your body's cells are like locks, and the key to unlocking a specific lock is a molecule that fits perfectly. Piperphenamine is like a key that fits into a specific lock, allowing it to turn and produce a response. This response can help to treat a variety of conditions, but the exact lock and key mechanism is still unknown.","oneSentence":"Piperphenamine is thought to work by interacting with a specific molecular target to produce its therapeutic effects.","technicalDetail":"Piperphenamine is a small molecule that likely interacts with a specific protein or receptor to produce its therapeutic effects, although the exact molecular mechanism is not well established."},"commercial":{},"references":[{"id":1,"url":"https://drugcentral.org/drugcard/1698","fields":["approvals","synonyms","ATC","PK","indications","contraindications","DDIs","targets","patents","FAERS"],"source":"DrugCentral"},{"id":2,"url":"https://pubmed.ncbi.nlm.nih.gov/?term=mepiperphenidol","fields":["publications"],"source":"PubMed/NCBI"}],"_enrichedAt":"2026-03-30T12:34:43.141211","biosimilars":[],"competitors":[],"genericName":"mepiperphenidol","indications":{"approved":[],"offLabel":[],"pipeline":[]},"drugCategory":"active","labelChanges":[],"relatedDrugs":[],"trialDetails":[],"genericFilers":[],"latestUpdates":[],"manufacturing":[],"crossReferences":{"NDDF":"001740","UNII":"8I07J24F45","CHEBI":"CHEBI:135211","UMLSCUI":"C0065962","ChEMBL_ID":"CHEMBL2078910","PUBCHEM_CID":"10620","SECONDARY_CAS_RN":"13004-75-6","MESH_SUPPLEMENTAL_RECORD_UI":"C010482"},"formularyStatus":[],"_enricherVersion":"v2","developmentCodes":[],"ownershipHistory":[],"publicationCount":39,"therapeuticAreas":["Other"],"biosimilarFilings":[],"recentPublications":[{"date":"2001 Sep","pmid":"11502595","title":"Interaction of cations, anions, and weak base quinine with rat renal cation transporter rOCT2 compared with rOCT1.","journal":"American journal of physiology. Renal physiology"},{"date":"2001 Jan","pmid":"11123374","title":"A novel zidovudine uptake system in microglia.","journal":"The Journal of pharmacology and experimental therapeutics"},{"date":"1998 Dec","pmid":"9864277","title":"Substrate specificity of organic cation/H+ exchange in avian renal brush-border membranes.","journal":"The Journal of pharmacology and experimental therapeutics"},{"date":"1997 Aug","pmid":"9262381","title":"Functional characterization of choroid plexus epithelial cells in primary culture.","journal":"The Journal of pharmacology and experimental therapeutics"},{"date":"1996 Dec","pmid":"9034623","title":"Precision-cut dog renal cortical slices in dynamic organ culture for the study of cisplatin nephrotoxicity.","journal":"Cell biology and toxicology"}],"companionDiagnostics":[],"genericManufacturerList":[],"status":"active","companyName":"","companyId":"unknown","modality":"Small Molecule","firstApprovalDate":"","aiSummary":"Piperphenamine, also known as mepiperphenidol, is a small molecule drug with unknown target and drug class. Its commercial status is unclear, and it is not FDA approved for any indications. As a research compound, it may be of interest to pharmaceutical professionals for its potential therapeutic applications. However, its safety profile and efficacy are not well established. Further research is needed to determine its potential as a therapeutic agent.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"partial","dataCompleteness":{"mechanism":true,"indications":false,"safety":false,"trials":false,"score":1}}