{"id":"mepartricin","rwe":[{"pmid":"39852945","year":"2025","title":"A Systematic Review of Medical Treatments for Benign Prostatic Hyperplasia in Dogs: Evaluating Strategies for Reproductive Function Preservation.","finding":"","journal":"Veterinary sciences","studyType":"Clinical Study"},{"pmid":"35970110","year":"2022","title":"Effect of mobile phase pH on liquid chromatography retention of mepartricin related compounds and impurities as support to the structural investigation by liquid chromatography-mass spectrometry.","finding":"","journal":"Journal of pharmaceutical and biomedical analysis","studyType":"Clinical Study"},{"pmid":"34577003","year":"2021","title":"Ipertrofan Revisited-The Proposal of the Complete Stereochemistry of Mepartricin A and B.","finding":"","journal":"Molecules (Basel, Switzerland)","studyType":"Clinical Study"},{"pmid":"31899937","year":"2020","title":"Pharmacological interventions for treating chronic prostatitis/chronic pelvic pain syndrome: a Cochrane systematic review.","finding":"","journal":"BJU international","studyType":"Clinical Study"},{"pmid":"26313612","year":"2015","title":"Chronic bacterial prostatitis and chronic pelvic pain syndrome.","finding":"","journal":"BMJ clinical evidence","studyType":"Clinical Study"}],"tags":[{"label":"mepartricin","category":"class"},{"label":"Small Molecule","category":"modality"},{"label":"A01AB16","category":"atc"},{"label":"Active","category":"status"},{"label":"Anti-Bacterial Agents","category":"pharmacology"},{"label":"Anti-Infective Agents","category":"pharmacology"},{"label":"Antifungal Agents","category":"pharmacology"},{"label":"Antiparasitic Agents","category":"pharmacology"},{"label":"Antiprotozoal Agents","category":"pharmacology"},{"label":"Urological Agents","category":"pharmacology"}],"phase":"phase_2","safety":{},"trials":[],"aliases":[],"patents":[],"pricing":[],"allNames":"methylpartricin","offLabel":[],"synonyms":["mepartricin","methylpartricin"],"timeline":[],"approvals":[],"brandName":"Methylpartricin","ecosystem":[],"mechanism":{"modality":"Small Molecule","drugClass":"mepartricin","explanation":"Imagine your body's cells are like a factory, and enzymes are the workers that help make important products. Mepartricin is like a tool that tries to stop one of these workers from doing their job, but we're not entirely sure which worker it targets or how it affects the factory's overall production.","oneSentence":"Mepartricin is thought to work by inhibiting a specific enzyme or pathway, but the exact mechanism is not well understood.","technicalDetail":"Mepartricin is a small molecule inhibitor that may interact with a specific enzyme or protein, but the precise molecular details of its mechanism of action are not well characterized."},"commercial":{},"references":[{"id":1,"url":"https://drugcentral.org/drugcard/4776","fields":["approvals","synonyms","ATC","PK","indications","contraindications","DDIs","targets","patents","FAERS"],"source":"DrugCentral"},{"id":2,"url":"https://pubmed.ncbi.nlm.nih.gov/?term=MEPARTRICIN","fields":["publications"],"source":"PubMed/NCBI"}],"_enrichedAt":"2026-03-30T12:34:27.828276","biosimilars":[],"competitors":[{"drugName":"hydrogen peroxide","drugSlug":"hydrogen-peroxide","fdaApproval":"","patentExpiry":"Jul 4, 2035","patentStatus":"Patent protected","relationship":"same-class"},{"drugName":"chlorhexidine","drugSlug":"chlorhexidine","fdaApproval":"1976-09-17","patentExpiry":"Oct 2, 2027","patentStatus":"Patent protected","relationship":"same-class"},{"drugName":"amphotericin B","drugSlug":"amphotericin-b","fdaApproval":"1964-11-12","genericCount":9,"patentStatus":"Off-patent — generic available","relationship":"same-class"},{"drugName":"oxyquinoline","drugSlug":"oxyquinoline","fdaApproval":"","relationship":"same-class"},{"drugName":"neomycin","drugSlug":"neomycin","fdaApproval":"1957-03-26","genericCount":12,"patentStatus":"Off-patent — generic available","relationship":"same-class"},{"drugName":"miconazole","drugSlug":"miconazole","fdaApproval":"1974-01-08","patentStatus":"Unknown","relationship":"same-class"},{"drugName":"natamycin","drugSlug":"natamycin","fdaApproval":"1978-10-30","patentStatus":"Unknown","relationship":"same-class"},{"drugName":"tetracycline","drugSlug":"tetracycline","fdaApproval":"1953-11-19","genericCount":34,"patentStatus":"Off-patent — generic available","relationship":"same-class"},{"drugName":"metronidazole","drugSlug":"metronidazole","fdaApproval":"1963-07-18","patentExpiry":"Oct 4, 2039","patentStatus":"Patent protected","relationship":"same-class"},{"drugName":"clotrimazole","drugSlug":"clotrimazole","fdaApproval":"1975-02-03","patentExpiry":"May 26, 2042","patentStatus":"Patent protected","relationship":"same-class"},{"drugName":"chlortetracycline","drugSlug":"chlortetracycline","fdaApproval":"1950-01-23","patentStatus":"Unknown","relationship":"same-class"},{"drugName":"doxycycline","drugSlug":"doxycycline","fdaApproval":"1967-12-05","patentExpiry":"Dec 19, 2027","patentStatus":"Patent protected","relationship":"same-class"},{"drugName":"minocycline","drugSlug":"minocycline","fdaApproval":"1971-06-30","patentExpiry":"Sep 8, 2037","patentStatus":"Patent protected","relationship":"same-class"},{"drugName":"oxytetracycline","drugSlug":"oxytetracycline","fdaApproval":"1964-09-08","patentStatus":"Unknown","relationship":"same-class"}],"genericName":"mepartricin","indications":{"approved":[],"offLabel":[],"pipeline":[]},"drugCategory":"active","labelChanges":[],"relatedDrugs":[{"drugId":"hydrogen-peroxide","brandName":"hydrogen peroxide","genericName":"hydrogen peroxide","approvalYear":"","relationship":"same-class"},{"drugId":"chlorhexidine","brandName":"chlorhexidine","genericName":"chlorhexidine","approvalYear":"1976","relationship":"same-class"},{"drugId":"amphotericin-b","brandName":"amphotericin B","genericName":"amphotericin B","approvalYear":"1964","relationship":"same-class"},{"drugId":"oxyquinoline","brandName":"oxyquinoline","genericName":"oxyquinoline","approvalYear":"","relationship":"same-class"},{"drugId":"neomycin","brandName":"neomycin","genericName":"neomycin","approvalYear":"1957","relationship":"same-class"},{"drugId":"miconazole","brandName":"miconazole","genericName":"miconazole","approvalYear":"1974","relationship":"same-class"},{"drugId":"natamycin","brandName":"natamycin","genericName":"natamycin","approvalYear":"1978","relationship":"same-class"},{"drugId":"tetracycline","brandName":"tetracycline","genericName":"tetracycline","approvalYear":"1953","relationship":"same-class"},{"drugId":"metronidazole","brandName":"metronidazole","genericName":"metronidazole","approvalYear":"1963","relationship":"same-class"},{"drugId":"clotrimazole","brandName":"clotrimazole","genericName":"clotrimazole","approvalYear":"1975","relationship":"same-class"}],"trialDetails":[],"genericFilers":[],"latestUpdates":[],"manufacturing":[],"crossReferences":{"UNII":"B7FBW3Y74G","INN_ID":"3864","UMLSCUI":"C0025373","ChEMBL_ID":"CHEMBL3989893","KEGG_DRUG":"D04921","DRUGBANK_ID":"DB13633","PUBCHEM_CID":"56842231","MESH_DESCRIPTOR_UI":"D008613"},"formularyStatus":[],"_enricherVersion":"v2","developmentCodes":[],"ownershipHistory":[],"publicationCount":94,"therapeuticAreas":["Other"],"atcClassification":{"source":"DrugCentral","atcCode":"A01AB16","allCodes":["A01AB16","D01AA06","G01AA09","G04CX03"]},"biosimilarFilings":[],"recentPublications":[{"date":"2025 Jan 19","pmid":"39852945","title":"A Systematic Review of Medical Treatments for Benign Prostatic Hyperplasia in Dogs: Evaluating Strategies for Reproductive Function Preservation.","journal":"Veterinary sciences"},{"date":"2022 Oct 25","pmid":"35970110","title":"Effect of mobile phase pH on liquid chromatography retention of mepartricin related compounds and impurities as support to the structural investigation by liquid chromatography-mass spectrometry.","journal":"Journal of pharmaceutical and biomedical analysis"},{"date":"2021 Sep 12","pmid":"34577003","title":"Ipertrofan Revisited-The Proposal of the Complete Stereochemistry of Mepartricin A and B.","journal":"Molecules (Basel, Switzerland)"},{"date":"2020 Apr","pmid":"31899937","title":"Pharmacological interventions for treating chronic prostatitis/chronic pelvic pain syndrome: a Cochrane systematic review.","journal":"BJU international"},{"date":"2015 Aug 27","pmid":"26313612","title":"Chronic bacterial prostatitis and chronic pelvic pain syndrome.","journal":"BMJ clinical evidence"}],"companionDiagnostics":[],"genericManufacturerList":[],"status":"active","companyName":"","companyId":"","modality":"Small Molecule","firstApprovalDate":"","aiSummary":"Mepartricin is a small molecule drug in the mepartricin class, but specific details about its development, commercial status, and approved indications are not available. As a result, there is limited information about its target, pharmacokinetics, and safety profile. Further research is needed to understand the clinical utility and potential risks associated with mepartricin. The current lack of information on its development and approval status suggests that it may not be a commercially available or widely used medication. More information is required to provide a comprehensive summary of mepartricin.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"partial","dataCompleteness":{"mechanism":true,"indications":false,"safety":false,"trials":false,"score":1}}