{"id":"meobentine","rwe":[{"pmid":"2434745","year":"1986","title":"Studies on bethanidine and meobentine: direct and indirect effects of antifibrillatory drugs.","finding":"","journal":"Journal of cardiovascular pharmacology","studyType":"Clinical Study"},{"pmid":"3901715","year":"1985","title":"Meobentine sulfate: antiarrhythmic and electrophysiologic effects assessed by programmed electrical stimulation and ambulatory monitoring in patients with complex ventricular tachyarrhythmia. Report of a multicenter evaluation.","finding":"","journal":"American heart journal","studyType":"Clinical Study"},{"pmid":"3986433","year":"1985","title":"A comparison of the effects of bethanidine, meobentine and quinidine on the electrical activity of rat hearts in vivo and in vitro.","finding":"","journal":"British journal of pharmacology","studyType":"Clinical Study"},{"pmid":"6206320","year":"1984","title":"The antiarrhythmic activity of meobentine sulfate in man.","finding":"","journal":"Journal of cardiovascular pharmacology","studyType":"Clinical Study"},{"pmid":"6720538","year":"1984","title":"Antidysrhythmic actions of meobentine sulfate.","finding":"","journal":"American heart journal","studyType":"Clinical Study"}],"tags":[{"label":"Small Molecule","category":"modality"},{"label":"Active","category":"status"}],"phase":"phase_2","safety":{},"trials":[],"aliases":[],"patents":[],"pricing":[],"allNames":["meobentine sulfate","meobentine"],"offLabel":[],"synonyms":["meobentine sulfate","meobentine"],"timeline":[],"approvals":[],"ecosystem":[],"mechanism":{"modality":"Small Molecule","explanation":"Imagine your body's cells are like a orchestra, and MEOBENTINE is like a conductor that helps the cells work together in harmony. By interacting with specific pathways, MEOBENTINE can help restore balance and function to the cells, leading to its therapeutic effect. However, the exact details of how it does this are still unknown.","oneSentence":"MEOBENTINE works by interacting with specific biological pathways to produce its therapeutic effect.","technicalDetail":"As a small molecule, MEOBENTINE likely works by binding to specific receptors or enzymes, altering the activity of downstream signaling pathways, and ultimately influencing the expression of genes involved in the disease process."},"commercial":{},"references":[{"id":1,"url":"https://drugcentral.org/drugcard/3340","fields":["approvals","synonyms","ATC","PK","indications","contraindications","DDIs","targets","patents","FAERS"],"source":"DrugCentral"},{"id":2,"url":"https://pubmed.ncbi.nlm.nih.gov/?term=MEOBENTINE","fields":["publications"],"source":"PubMed/NCBI"}],"_enrichedAt":"2026-03-30T12:34:24.157120","biosimilars":[],"competitors":[],"genericName":"meobentine","indications":{"approved":[],"offLabel":[],"pipeline":[]},"drugCategory":"active","labelChanges":[],"relatedDrugs":[],"trialDetails":[],"genericFilers":[],"latestUpdates":[],"manufacturing":[],"crossReferences":{"UNII":"T91E239Z1V","CHEBI":"CHEBI:134874","INN_ID":"4194","UMLSCUI":"C0065952","ChEMBL_ID":"CHEMBL2110972","KEGG_DRUG":"D04920","PUBCHEM_CID":"42765","SECONDARY_CAS_RN":"58503-79-0","MESH_SUPPLEMENTAL_RECORD_UI":"C032896"},"formularyStatus":[],"_enricherVersion":"v2","developmentCodes":[],"ownershipHistory":[],"publicationCount":7,"therapeuticAreas":["Other"],"biosimilarFilings":[],"recentPublications":[{"date":"1986 Nov-Dec","pmid":"2434745","title":"Studies on bethanidine and meobentine: direct and indirect effects of antifibrillatory drugs.","journal":"Journal of cardiovascular pharmacology"},{"date":"1985 Oct","pmid":"3901715","title":"Meobentine sulfate: antiarrhythmic and electrophysiologic effects assessed by programmed electrical stimulation and ambulatory monitoring in patients with complex ventricular tachyarrhythmia. Report of a multicenter evaluation.","journal":"American heart journal"},{"date":"1985 Mar","pmid":"3986433","title":"A comparison of the effects of bethanidine, meobentine and quinidine on the electrical activity of rat hearts in vivo and in vitro.","journal":"British journal of pharmacology"},{"date":"1984 Jul-Aug","pmid":"6206320","title":"The antiarrhythmic activity of meobentine sulfate in man.","journal":"Journal of cardiovascular pharmacology"},{"date":"1984 Jun","pmid":"6720538","title":"Antidysrhythmic actions of meobentine sulfate.","journal":"American heart journal"}],"companionDiagnostics":[],"genericManufacturerList":[],"status":"active","brandName":"MEOBENTINE","companyName":"","companyId":"","modality":"Small molecule","firstApprovalDate":"","aiSummary":"MEOBENTINE is a small molecule drug with unknown target and drug class. Its commercial status is unclear, and it has not been approved by the FDA for any indications. As a small molecule, it is likely to work by interacting with specific biological pathways, but the exact mechanism is unknown. Further research is needed to determine its efficacy and safety profile. Its development and ownership history are also unclear.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"partial","dataCompleteness":{"mechanism":true,"indications":false,"safety":false,"trials":false,"score":1}}