{"id":"mentor-purified-toxin","safety":{"commonSideEffects":[{"rate":null,"effect":"Injection site pain or bruising"},{"rate":null,"effect":"Headache"},{"rate":null,"effect":"Muscle weakness or paralysis (off-target)"},{"rate":null,"effect":"Antibody formation (immunogenicity)"}]},"_chembl":{"chemblId":"CHEMBL4176158","moleculeType":"Small molecule","molecularWeight":"320.34"},"_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"Botulinum toxin is a neurotoxin that irreversibly cleaves proteins required for acetylcholine vesicle fusion and release at the neuromuscular junction. This results in temporary paralysis of muscles at the injection site. Mentor Worldwide's purified formulation is designed to minimize immunogenicity while maintaining therapeutic efficacy for cosmetic and medical applications.","oneSentence":"Mentor Purified Toxin is a botulinum toxin preparation that blocks acetylcholine release at the neuromuscular junction by cleaving SNARE proteins.","_ai_confidence":"medium"},"_scrapedAt":"2026-03-28T01:20:44.884Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Facial wrinkles and dynamic expression lines (cosmetic indication)"},{"name":"Cervical dystonia, blepharospasm, and other movement disorders (medical indication)"}]},"trialDetails":[{"nctId":"NCT00549341","phase":"PHASE1","title":"PurTox (Botulinum Toxin Type A) for the Treatment of Adult Onset Spasmodic Torticollis/Cervical Dystonia","status":"COMPLETED","sponsor":"Mentor Worldwide, LLC","startDate":"2006-05","conditions":"Spasmodic Torticollis","enrollment":70},{"nctId":"NCT00752297","phase":"PHASE3","title":"Safety and Efficacy Study of PurTox® Botulinum Toxin Type A to Treat Frown Lines Between the Eyebrows","status":"COMPLETED","sponsor":"Mentor Worldwide, LLC","startDate":"2007-06","conditions":"Glabellar Rhytides","enrollment":402},{"nctId":"NCT00752050","phase":"PHASE3","title":"Safety and Efficacy Study of Repeat Treatment With PurTox® Botulinum Toxin Type A for Frown Lines Between the Eyebrows","status":"COMPLETED","sponsor":"Mentor Worldwide, LLC","startDate":"2007-11","conditions":"Glabellar Rhytides, Frown Lines Between the Eyebrows","enrollment":699},{"nctId":"NCT00752258","phase":"PHASE3","title":"A Long-Term Safety Study of Repeat Treatment With PurTox® for Frown Lines Between the Eyebrows","status":"COMPLETED","sponsor":"Mentor Worldwide, LLC","startDate":"2008-02","conditions":"Glabellar Rhytides","enrollment":576}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":0,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":["Arms: 1","Other Names:","Mentor Purified Toxin Botulinum Toxin Type A","Botulinum Toxin Type A","Botulinum Toxin"],"phase":"phase_3","status":"active","brandName":"Mentor Purified Toxin","genericName":"Mentor Purified Toxin","companyName":"Mentor Worldwide, LLC","companyId":"mentor-worldwide-llc","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Mentor Purified Toxin is a botulinum toxin preparation that blocks acetylcholine release at the neuromuscular junction by cleaving SNARE proteins. Used for Facial wrinkles and dynamic expression lines (cosmetic indication), Cervical dystonia, blepharospasm, and other movement disorders (medical indication).","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}