{"id":"mega-resveratrol-capsules","safety":{"commonSideEffects":[{"rate":null,"effect":"Gastrointestinal upset"},{"rate":null,"effect":"Headache"},{"rate":null,"effect":"Nausea"}]},"_chembl":null,"_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"Resveratrol is a naturally occurring polyphenol found in grapes and red wine that functions primarily through antioxidant activity and activation of sirtuins (NAD+-dependent deacetylases), particularly SIRT1. These mechanisms promote cellular stress resistance, mitochondrial function, and anti-inflammatory responses. The compound also modulates multiple signaling pathways including AMPK and NF-κB, contributing to potential cardioprotective, neuroprotective, and anti-aging effects.","oneSentence":"Resveratrol acts as a polyphenolic antioxidant and sirtuin activator that reduces oxidative stress and modulates cellular signaling pathways involved in aging and disease.","_ai_confidence":"low"},"_scrapedAt":"2026-03-28T01:20:34.144Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Cardiovascular health and endothelial function"},{"name":"Age-related cognitive decline and neuroprotection"}]},"trialDetails":[{"nctId":"NCT04886297","phase":"PHASE3","title":"A Dose-response Study of Dietary Resveratrol on Lipid Metabolism Disorder","status":"COMPLETED","sponsor":"Sun Yat-sen University","startDate":"2021-05-01","conditions":"Dyslipidemias","enrollment":168}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":0,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":[],"phase":"phase_3","status":"active","brandName":"Mega Resveratrol® capsules","genericName":"Mega Resveratrol® capsules","companyName":"Sun Yat-sen University","companyId":"sun-yat-sen-university","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Resveratrol acts as a polyphenolic antioxidant and sirtuin activator that reduces oxidative stress and modulates cellular signaling pathways involved in aging and disease. Used for Cardiovascular health and endothelial function, Age-related cognitive decline and neuroprotection.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":1,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}