{"id":"medicinal-honey","safety":{"commonSideEffects":[{"rate":null,"effect":"Local irritation or stinging"},{"rate":null,"effect":"Allergic reaction (rare)"}]},"_chembl":{"chemblId":"CHEMBL2108391","moleculeType":"Unknown"},"_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"Honey contains glucose oxidase, which produces hydrogen peroxide when diluted, creating a mild antimicrobial environment. Its high osmolarity draws fluid from wounds, reducing edema and bacterial growth. Additionally, honey contains polyphenols, flavonoids, and other bioactive compounds that provide antioxidant and anti-inflammatory effects, supporting tissue repair and reducing infection risk.","oneSentence":"Medicinal honey promotes wound healing and antimicrobial activity through enzymatic production of hydrogen peroxide, osmotic effects, and bioactive compounds.","_ai_confidence":"medium"},"_scrapedAt":"2026-03-28T00:41:19.926Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Wound healing and management"},{"name":"Burn care"},{"name":"Ulcer treatment"}]},"trialDetails":[{"nctId":"NCT06859424","phase":"PHASE2","title":"A Platform Protocol to Investigate Post-Transplant Cyclophosphamide-Based Graft-Versus-Host Disease Prophylaxis in Patients With Hematologic Malignancies Undergoing Mismatched Unrelated Donor Peripheral Blood Stem Cell Transplantation","status":"RECRUITING","sponsor":"Center for International Blood and Marrow Transplant Research","startDate":"2025-07-25","conditions":"AML (Acute Myelogenous Leukemia), Acute Lymphoid Leukemia (ALL), Acute Leukemia (Category)","enrollment":358},{"nctId":"NCT03929224","phase":"PHASE4","title":"The Use of Medical Grade Honey in the Prevention of Bone Anchored Hearing Aid Associated Skin Breakdown","status":"COMPLETED","sponsor":"Henry Ford Health System","startDate":"2018-10-25","conditions":"Skin Infection","enrollment":17},{"nctId":"NCT06629246","phase":"NA","title":"Pogejiuxin Decoction Combination of Conventional Western Medicine for the Treatment of Heart Failure with Preserved Ejection Fraction","status":"COMPLETED","sponsor":"Chongqing Traditional Chinese Medicine Hospital","startDate":"2021-09-01","conditions":"Heart Failure, Diastolic (HFpEF)","enrollment":100},{"nctId":"NCT02482948","phase":"NA","title":"MEDIHONEY® Gel Versus Collagenase for Wound Debridement","status":"TERMINATED","sponsor":"Integra LifeSciences Corporation","startDate":"2015-06","conditions":"Ulcer, Wounds","enrollment":10}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":32,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":["MEDIHONEY"],"phase":"marketed","status":"active","brandName":"Medicinal honey","genericName":"Medicinal honey","companyName":"Henry Ford Health System","companyId":"henry-ford-health-system","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Medicinal honey promotes wound healing and antimicrobial activity through enzymatic hydrogen peroxide production, osmotic effects, and direct antibacterial compounds. Used for Wound healing and management, Burn care, Diabetic foot ulcers.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":1,"withResults":1},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}