{"id":"medicabilis-cbd-oil","safety":{"commonSideEffects":[{"rate":null,"effect":"Drowsiness"},{"rate":null,"effect":"Fatigue"},{"rate":null,"effect":"Diarrhea"},{"rate":null,"effect":"Changes in appetite"},{"rate":null,"effect":"Headache"}]},"_chembl":null,"_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"Cannabidiol acts as a negative allosteric modulator of CB1 and CB2 receptors and interacts with serotonin (5-HT1A), vanilloid (TRPV1), and other receptors to reduce inflammation, anxiety, and pain signaling. The exact mechanisms vary by indication and are not fully elucidated, but CBD does not produce the psychoactive effects associated with THC.","oneSentence":"CBD (cannabidiol) modulates endocannabinoid system signaling and interacts with multiple receptors to produce anti-inflammatory, anxiolytic, and analgesic effects.","_ai_confidence":"medium"},"_scrapedAt":"2026-03-27T23:54:17.064Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Chronic pain"},{"name":"Anxiety"},{"name":"Epilepsy (seizure disorders)"},{"name":"Inflammation-related conditions"}]},"trialDetails":[{"nctId":"NCT03690791","phase":"PHASE3","title":"Efficacy of Cannabinoids in Amyotrophic Lateral Sclerosis or Motor Neurone Disease","status":"UNKNOWN","sponsor":"Gold Coast Hospital and Health Service","startDate":"2019-01-09","conditions":"Amyotrophic Lateral Sclerosis, Motor Neuron Disease","enrollment":17},{"nctId":"NCT04997954","phase":"PHASE4","title":"EMERALD TRIAL Open Label Extension Study","status":"UNKNOWN","sponsor":"Gold Coast Hospital and Health Service","startDate":"2021-05-17","conditions":"Amyotrophic Lateral Sclerosis, Cannabis, CBD","enrollment":7}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":1,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":[],"phase":"marketed","status":"active","brandName":"MediCabilis CBD Oil","genericName":"MediCabilis CBD Oil","companyName":"Gold Coast Hospital and Health Service","companyId":"gold-coast-hospital-and-health-service","modality":"Small molecule","firstApprovalDate":"","aiSummary":"CBD (cannabidiol) modulates endocannabinoid system signaling and interacts with multiple receptors to produce anti-inflammatory, anxiolytic, and analgesic effects. Used for Chronic pain, Anxiety, Epilepsy (seizure disorders).","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":1,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}