{"id":"mct-lct-1-1","safety":{"commonSideEffects":[{"rate":null,"effect":"Hypertriglyceridemia"},{"rate":null,"effect":"Infusion site reactions"},{"rate":null,"effect":"Hepatic steatosis (with prolonged use)"},{"rate":null,"effect":"Allergic reactions"}]},"_chembl":null,"_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"This intravenous lipid emulsion combines MCTs (medium-chain triglycerides), which are rapidly metabolized and provide quick energy, with LCTs (long-chain triglycerides), which provide essential fatty acids and longer-term energy substrate. The 1:1 ratio is designed to optimize both rapid energy availability and essential fatty acid provision while potentially reducing metabolic complications associated with pure LCT or pure MCT formulations.","oneSentence":"MCT/LCT (1:1) is a lipid emulsion that provides a balanced mixture of medium-chain triglycerides and long-chain triglycerides for parenteral nutrition.","_ai_confidence":"medium"},"_scrapedAt":"2026-03-27T23:54:10.345Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Parenteral nutrition in patients unable to receive adequate oral or enteral nutrition"},{"name":"Provision of essential fatty acids and energy in critically ill or post-operative patients"}]},"trialDetails":[{"nctId":"NCT02578394","phase":"PHASE2, PHASE3","title":"Anakinra vs. Steroids for the Treatment of Gout Attacks in Patients With Renal Disease (ASGARD): A Feasibility Study","status":"COMPLETED","sponsor":"Mid and South Essex NHS Foundation Trust","startDate":"2016-04","conditions":"Gout, Chronic Kidney Diseases","enrollment":21},{"nctId":"NCT00497289","phase":"PHASE2","title":"Comparison of Two Different Lipid Emulsions for Parenteral Nutrition in Preterm Infants","status":"COMPLETED","sponsor":"B. Braun Melsungen AG","startDate":"2006-01","conditions":"Preterm Infants, Parenteral Nutrition n-3 Fatty Acids","enrollment":48},{"nctId":"NCT04511299","phase":"NA","title":"Impact of Fish Oil-enriched Lipid Emulsion on Fatty Acid and Inflammatory Response in Infants After Surgery","status":"COMPLETED","sponsor":"Dr. Soetomo General Hospital","startDate":"2020-04-07","conditions":"Surgery","enrollment":12},{"nctId":"NCT04277923","phase":"PHASE4","title":"Effects of Fat Emulsions on PNALD and Oxidative Stress in Premature Infants","status":"UNKNOWN","sponsor":"Shanghai Jiao Tong University School of Medicine","startDate":"2020-02","conditions":"Preterm Infant","enrollment":66},{"nctId":"NCT01814956","phase":"PHASE4","title":"Different Lipid Emulsions in Acute Lung Injury Patients","status":"TERMINATED","sponsor":"B. Braun Melsungen AG","startDate":"2013-03","conditions":"Parenteral Nutrition","enrollment":1},{"nctId":"NCT00396461","phase":"PHASE4","title":"ICULIP, Influence of Two Lipid Emulsions in the Nosocomial Infection in Critical Patients","status":"TERMINATED","sponsor":"B. Braun Medical SA","startDate":"2006-11","conditions":"Critical Illness","enrollment":212},{"nctId":"NCT01683162","phase":"PHASE4","title":"Effects of Parenteral Nutrition With Different Lipid Emulsions in Preterm Infants","status":"UNKNOWN","sponsor":"Wei Cai","startDate":"2012-07","conditions":"Preterm Infant","enrollment":150},{"nctId":"NCT01176695","phase":"PHASE3","title":"Efficacy and Safety of a Fish Oil Containing Lipid Emulsion","status":"COMPLETED","sponsor":"B. Braun Melsungen AG","startDate":"2010-04","conditions":"Parenteral Nutrition","enrollment":240},{"nctId":"NCT01376817","phase":"PHASE4","title":"Comparative Study About the Impact of Two Oil Emulsions Administered Intravenously on Severe Acute Pancreatitis","status":"UNKNOWN","sponsor":"Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau","startDate":"2008-07","conditions":"Severe Acute Pancreatitis","enrollment":60},{"nctId":"NCT00207233","phase":"PHASE1, PHASE2","title":"Use of MCT Oil for Enhancement of Weight Loss and Glycemic Control in Obese Diabetic Patients","status":"COMPLETED","sponsor":"Boston Medical Center","startDate":"2004-07","conditions":"Obesity, Type 2 Diabetes Mellitus","enrollment":42},{"nctId":"NCT00798681","phase":"PHASE4","title":"Evaluating the Influence of Ready-to-use (RTU) Parenteral Nutrition in the Clinical Outcome of Patients Study","status":"COMPLETED","sponsor":"Fernandes Tavora Hospital","startDate":"2008-07","conditions":"Parenteral Nutrition","enrollment":406},{"nctId":"NCT00506246","phase":"PHASE3","title":"Efficacy and Safety Study of Two Propofol Formulations","status":"COMPLETED","sponsor":"B. Braun Melsungen AG","startDate":"2007-06","conditions":"General Anaesthesia, Induction of Anaesthesia","enrollment":220},{"nctId":"NCT00558155","phase":"PHASE4","title":"The Impact of Immunostimulating Nutrition on the Outcome of Surgery","status":"COMPLETED","sponsor":"Jagiellonian University","startDate":"2001-06","conditions":"Gastric Cancer, Pancreatic Cancer","enrollment":214}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":5,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":["LIPOFUNDINA"],"phase":"marketed","status":"active","brandName":"MCT/LCT (1:1)","genericName":"MCT/LCT (1:1)","companyName":"B. Braun Medical SA","companyId":"b-braun-medical-sa","modality":"Small molecule","firstApprovalDate":"","aiSummary":"MCT/LCT (1:1) is a lipid emulsion that provides a balanced mixture of medium-chain triglycerides and long-chain triglycerides for parenteral nutrition. Used for Parenteral nutrition in patients unable to receive adequate enteral nutrition, Source of calories and essential fatty acids in clinical nutrition support.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}