{"id":"master-formula-of-aloe-vera-gel-80","safety":{"commonSideEffects":[{"rate":null,"effect":"Contact dermatitis or allergic reaction"},{"rate":null,"effect":"Skin irritation at application site"}]},"_chembl":{"chemblId":"CHEMBL3989763","moleculeType":"Oligosaccharide","molecularWeight":"1692.49"},"_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"Aloe vera contains multiple active constituents including acemannan (a polysaccharide), aloin, and various amino acids that stimulate fibroblast activity, enhance collagen synthesis, and promote epithelialization. The gel also exhibits antimicrobial and anti-inflammatory properties that support the healing process and reduce bacterial colonization of wounds. These mechanisms make it suitable for topical application in wound care, burns, and dermatological conditions.","oneSentence":"Aloe vera gel provides topical wound healing and anti-inflammatory effects through polysaccharides, anthraquinones, and other bioactive compounds that promote tissue repair and reduce inflammation.","_ai_confidence":"medium"},"_scrapedAt":"2026-03-27T23:53:54.348Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Wound healing and minor burns"},{"name":"Skin irritation and inflammation"},{"name":"Topical dermatological conditions"}]},"trialDetails":[{"nctId":"NCT03633292","phase":"PHASE4","title":"Aloe Vera and Chlorhexidine Against Traumatic Oral Ulcers","status":"COMPLETED","sponsor":"University of Santiago de Compostela","startDate":"2015-01","conditions":"Oral Ulcer","enrollment":140}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":1,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":[],"phase":"marketed","status":"active","brandName":"Master formula of aloe vera gel 80%","genericName":"Master formula of aloe vera gel 80%","companyName":"University of Santiago de Compostela","companyId":"university-of-santiago-de-compostela","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Aloe vera gel provides topical wound healing and anti-inflammatory effects through polysaccharides, anthraquinones, and other bioactive compounds that promote tissue repair and reduce inflammation. Used for Wound healing and tissue repair, Minor burns and skin irritation, Topical anti-inflammatory treatment.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}