{"id":"markman-biologics-microsurfaced-adm","safety":{"commonSideEffects":[{"rate":null,"effect":"Infection"},{"rate":null,"effect":"Seroma formation"},{"rate":null,"effect":"Graft failure or poor integration"},{"rate":null,"effect":"Inflammatory response"}]},"_chembl":null,"_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"This is a biologic scaffold derived from human cadaveric skin with the cellular components removed, leaving behind the extracellular matrix. The microsurfacing technology modifies the surface properties to enhance tissue integration, reduce inflammatory response, and improve vascularization when used in reconstructive and plastic surgical applications.","oneSentence":"Markman Biologics Microsurfaced ADM is an acellular dermal matrix (ADM) product with a modified surface designed to improve integration and reduce complications in reconstructive surgery.","_ai_confidence":"low"},"_scrapedAt":"2026-03-27T23:54:01.939Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Soft tissue reconstruction and augmentation in plastic and reconstructive surgery"},{"name":"Burn wound coverage and reconstruction"}]},"trialDetails":[{"nctId":"NCT04614350","phase":"PHASE4","title":"Pilot Study for Healing and Safety Outcomes in Gingival Recession","status":"COMPLETED","sponsor":"McGuire Institute","startDate":"2020-10-30","conditions":"Gingival Recession","enrollment":10}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":0,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":[],"phase":"marketed","status":"active","brandName":"Markman Biologics Microsurfaced ADM","genericName":"Markman Biologics Microsurfaced ADM","companyName":"McGuire Institute","companyId":"mcguire-institute","modality":"Biologic","firstApprovalDate":"","aiSummary":"Markman Biologics Microsurfaced ADM is an acellular dermal matrix (ADM) product with a modified surface designed to improve integration and reduce complications in reconstructive and aesthetic surgical applications. Used for Soft tissue reconstruction and augmentation in plastic and reconstructive surgery, Breast reconstruction, Abdominal wall reconstruction.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":1,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}