{"id":"mak","safety":{"commonSideEffects":[]},"_chembl":{"chemblId":"CHEMBL4650489","moleculeType":"Unknown"},"_dailymed":{"setId":"db87d81c-bd6c-47dd-8d4c-61b6b1155ce8","title":"GENTLE EYE MAKEUP REMOVER (BENZALKONIUM CHLORIDE) LIQUID [LONGWAY TECHNOLOGY(GUANGZHOU) CO., LTD]"},"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"MAK (Maharishi Amrit Kalash) is a polyherbal Ayurvedic preparation consisting of multiple plant-derived ingredients. It is marketed as an adaptogenic and antioxidant formulation intended to promote general health and longevity. The specific molecular mechanisms have not been rigorously characterized in conventional pharmaceutical terms.","oneSentence":"MAK is a traditional Ayurvedic herbal formulation that is proposed to support overall wellness and balance according to Ayurvedic principles.","_ai_confidence":"low"},"_scrapedAt":"2026-03-28T01:59:06.715Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"General wellness and health promotion (Ayurvedic indication)"}]},"trialDetails":[{"nctId":"NCT07490223","phase":"","title":"Self-Efficacy and Academic Burnout Among Sports Science Undergraduates in Indonesia","status":"COMPLETED","sponsor":"Hasanuddin University","startDate":"2025-03-01","conditions":"Burnout Syndrome, Self Efficacy","enrollment":233},{"nctId":"NCT07206901","phase":"NA","title":"Evaluation of an Ayurvedic Herbal Compound Compared to Vitamins C+E and Placebo on Vascular Function in High-Risk Subjects","status":"COMPLETED","sponsor":"Maharishi International University","startDate":"2002-10-14","conditions":"Coronary Artery Disease","enrollment":143},{"nctId":"NCT06320743","phase":"NA","title":"Cerebral and Peripheral Near Infrared Spectroscopy Monitoring in Low and High Flow Anaesthesia in Pediatric","status":"COMPLETED","sponsor":"Ankara City Hospital Bilkent","startDate":"2024-03-20","conditions":"Child, Only, Inhalation; Vapor, Anesthesia","enrollment":66},{"nctId":"NCT05411536","phase":"","title":"Attentional Focus Instructions and Conscious Movement Processing in Older Adults","status":"UNKNOWN","sponsor":"The Hong Kong Polytechnic University","startDate":"2022-07-15","conditions":"Fall Injury, Walking, Difficulty, Gait, Unsteady","enrollment":106},{"nctId":"NCT05242757","phase":"NA","title":"Clinical Study of MAK Immune Cells in the Treatment of PHC","status":"UNKNOWN","sponsor":"Zhongnan Hospital","startDate":"2021-01-01","conditions":"Primary Hepatocellular Carcinoma","enrollment":12},{"nctId":"NCT05240690","phase":"PHASE1","title":"Umbilical Cord Blood Derived MAK Immune Cells Combined With Standard Second-Line Treatments for Hepatobiliary and Pancreatic Malignancies","status":"UNKNOWN","sponsor":"Zhou Fuxiang","startDate":"2022-02-07","conditions":"Stage IV Pancreatic Cancer, Hepatocellular Carcinoma , Cholangiocarcinoma","enrollment":27},{"nctId":"NCT04310748","phase":"NA","title":"Effects of TIVA and Inhalation Anesthesia on Oxidative Stress Factors During Hypotensive Anesthesia","status":"COMPLETED","sponsor":"Bezmialem Vakif University","startDate":"2020-05-01","conditions":"Oxidative Stress, Anesthesia","enrollment":60},{"nctId":"NCT04743193","phase":"","title":"Different Low-flow Sevoflurane Anesthesia Techniques","status":"COMPLETED","sponsor":"Kocaeli Derince Education and Research Hospital","startDate":"2021-02-05","conditions":"Anesthesia","enrollment":60},{"nctId":"NCT04837144","phase":"NA","title":"Evaluation of the Safety and Usability of the MAK Exoskeleton in Patients With Stroke","status":"COMPLETED","sponsor":"MarsiBionics","startDate":"2020-10-06","conditions":"Stroke, Gait, Hemiplegic","enrollment":6},{"nctId":"NCT02420249","phase":"NA","title":"Qigong for Breast Cancer Survivors","status":"UNKNOWN","sponsor":"The University of Hong Kong","startDate":"2015-03","conditions":"Neoplasms","enrollment":60},{"nctId":"NCT00010725","phase":"PHASE2","title":"Effects of Herbal Antioxidants on Cardiovascular Disease in Older Blacks","status":"COMPLETED","sponsor":"National Center for Complementary and Integrative Health (NCCIH)","startDate":"1999-09","conditions":"Cardiovascular Diseases","enrollment":138},{"nctId":"NCT00785174","phase":"PHASE3","title":"Non-Invasive Ventilation Versus Continuous Positive Airway Pressure in Cardiogenic Pulmonary Edema: a Multicentre Study","status":"COMPLETED","sponsor":"University of Monastir","startDate":"2005-01","conditions":"Cardiogenic Pulmonary Edema","enrollment":200}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":0,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":[],"phase":"marketed","status":"active","brandName":"MAK","genericName":"MAK","companyName":"National Center for Complementary and Integrative Health (NCCIH)","companyId":"national-center-for-complementary-and-integrative-health-nccih","modality":"Small molecule","firstApprovalDate":"","aiSummary":"MAK is a traditional Ayurvedic herbal formulation that is proposed to support overall wellness and balance according to Ayurvedic principles. Used for General wellness and rejuvenation (Ayurvedic indication).","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":false,"trials":true,"score":3}}