{"id":"magnesium-sulfate-iv","safety":{"commonSideEffects":[{"rate":null,"effect":"Flushing"},{"rate":null,"effect":"Hypotension"},{"rate":null,"effect":"Hypermagnesemia (with overdose)"},{"rate":null,"effect":"Loss of deep tendon reflexes"},{"rate":null,"effect":"Muscle weakness"},{"rate":null,"effect":"Respiratory depression (at high doses)"}]},"_chembl":{"chemblId":"CHEMBL3989857","moleculeType":"Small molecule","molecularWeight":"246.47"},"_fixedAt":"2026-03-30T17:12:47.707489","_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"Magnesium ions compete with calcium for entry into cells and block NMDA-type glutamate receptors, thereby reducing excitatory neurotransmission. This mechanism underlies its use in preventing seizures (particularly eclampsia/pre-eclampsia), treating cardiac arrhythmias, and providing bronchodilation in acute asthma. 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