{"id":"magnesium-phosphate","rwe":[{"pmid":"41900551","year":"2026","title":"A Novel Approach to Optimize the Rheology and Buildability of 3D-Printed Magnesium Phosphate Cement Composites Using Carbonated Recycled Aggregate.","finding":"","journal":"Materials (Basel, Switzerland)","studyType":"Clinical Study"},{"pmid":"41894009","year":"2026","title":"A novel magnesium phosphate cement paste enables effective augmentation of pedicle screws in osteoporotic bone.","finding":"","journal":"International orthopaedics","studyType":"Clinical Study"},{"pmid":"41893189","year":"2026","title":"Influence of Treated Surface Proportion on the Antibacterial Performance of UV-Activated Hydroxyapatite-Magnesium Phosphate-Zinc Oxide Coating on Magnesium Alloys.","finding":"","journal":"Journal of functional biomaterials","studyType":"Clinical Study"},{"pmid":"41835087","year":"2026","title":"An all-in-one injectable biocement: self-setting magnesium phosphate for bone repair, fracture adhesion and osteoporotic fixation.","finding":"","journal":"Regenerative biomaterials","studyType":"Clinical Study"},{"pmid":"41830278","year":"2026","title":"[Effects of Amendments and Straw Return on Soil and Rice Cd Content in a Rice/Rape Rotation System].","finding":"","journal":"Huan jing ke xue= Huanjing kexue","studyType":"Clinical Study"}],"tags":[{"label":"magnesium phosphate","category":"class"},{"label":"Small Molecule","category":"modality"},{"label":"B05XA10","category":"atc"},{"label":"Active","category":"status"}],"phase":"unknown","safety":{},"trials":[],"aliases":[],"patents":[],"pricing":[],"allNames":"magnesium orthophosphate","offLabel":[],"synonyms":["magnesium phosphate","magnesium orthophosphate"],"timeline":[],"approvals":[],"brandName":"Magnesium Orthophosphate","ecosystem":[],"mechanism":{"modality":"Small Molecule","drugClass":"magnesium phosphate","explanation":"Imagine your body's cells have locks that need a specific key to open. Magnesium Orthophosphate is like a key that fits into these locks, allowing the cell to function properly. This can help to regulate various bodily functions, but more research is needed to understand exactly how it works.","oneSentence":"Magnesium Orthophosphate works by binding to phosphate groups in the body, potentially influencing various cellular processes.","technicalDetail":"Magnesium Orthophosphate is a magnesium salt of orthophosphoric acid, which binds to phosphate groups in the body, potentially influencing various cellular processes through its effects on ATP production, protein function, and gene expression."},"_wikipedia":{"url":"https://en.wikipedia.org/wiki/Magnesium_phosphate","title":"Magnesium phosphate","extract":"Magnesium phosphate is a general term for salts of magnesium and phosphate appearing in several forms and several hydrates:Monomagnesium phosphate:   Mg(H2PO4)2·nH2O\nDimagnesium phosphate:   Mg(HPO4)·nH2O\nTrimagnesium phosphate:   Mg3(PO4)2·nH2O"},"commercial":{},"references":[{"id":1,"url":"https://drugcentral.org/drugcard/4596","fields":["approvals","synonyms","ATC","PK","indications","contraindications","DDIs","targets","patents","FAERS"],"source":"DrugCentral"},{"id":2,"url":"https://clinicaltrials.gov/search?intr=magnesium%20phosphate","fields":["trials"],"source":"ClinicalTrials.gov"},{"id":3,"url":"https://pubmed.ncbi.nlm.nih.gov/?term=magnesium phosphate","fields":["publications"],"source":"PubMed/NCBI"},{"id":4,"url":"https://en.wikipedia.org/wiki/Magnesium_phosphate","fields":["history","overview"],"source":"Wikipedia"}],"_enrichedAt":"2026-03-30T15:00:57.003305","biosimilars":[],"competitors":[{"drugName":"potassium chloride","drugSlug":"potassium-chloride","fdaApproval":"1965-12-16","patentExpiry":"Mar 7, 2039","patentStatus":"Patent protected","relationship":"same-class"},{"drugName":"sodium 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acetate","drugSlug":"sodium-acetate","fdaApproval":"1983-05-04","genericCount":5,"patentStatus":"Off-patent — generic available","relationship":"same-class"},{"drugName":"sodium phosphate","drugSlug":"sodium-phosphate","fdaApproval":"1983-05-10","patentStatus":"Unknown","relationship":"same-class"},{"drugName":"magnesium chloride","drugSlug":"magnesium-chloride","fdaApproval":"1975-08-13","relationship":"same-class"},{"drugName":"zinc chloride","drugSlug":"zinc-chloride","fdaApproval":"1986-06-26","genericCount":3,"patentStatus":"Off-patent — generic available","relationship":"same-class"},{"drugName":"sodium glycerophosphate","drugSlug":"sodium-glycerophosphate","fdaApproval":"2014-08-25","relationship":"same-class"},{"drugName":"potassium lactate","drugSlug":"potassium-lactate","fdaApproval":"1986-05-08","relationship":"same-class"},{"drugName":"potassium acetate","drugSlug":"potassium-acetate","fdaApproval":"1971-09-24","genericCount":2,"patentStatus":"Off-patent — generic 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Function in Overweight Men","status":"COMPLETED","sponsor":"Griffin Hospital","startDate":"2009-07","conditions":["Overweight and Obesity"],"enrollment":70,"completionDate":"2010-08"},{"nctId":"NCT00844662","phase":"PHASE3","title":"Phase III Study to Investigate the Safety and Efficacy of Fermagate and Sevelamer Hydrochloride","status":"TERMINATED","sponsor":"Ineos Healthcare Limited","startDate":"2009-07","conditions":["Chronic Kidney Failure"],"enrollment":1000,"completionDate":"2011-10"},{"nctId":"NCT00841126","phase":"PHASE3","title":"Phase III Study to Investigate the Safety and Efficacy of Fermagate and Lanthanum Carbonate","status":"TERMINATED","sponsor":"Ineos Healthcare Limited","startDate":"2009-07","conditions":["Chronic Kidney Failure"],"enrollment":657,"completionDate":"2011-07"},{"nctId":"NCT00317694","phase":"PHASE2","title":"Efficacy and Safety Study of Magnesium Iron Hydroxycarbonate for the Reduction of High Blood Phosphate in Hemodialysis Patients","status":"COMPLETED","sponsor":"Ineos Healthcare Limited","startDate":"2006-03","conditions":["Chronic Kidney Failure"],"enrollment":111,"completionDate":"2007-06"},{"nctId":"NCT00436683","phase":"PHASE2","title":"Dose Ranging Study of Magnesium Iron Hydroxycarbonate in Haemodialysis Subjects With Hyperphosphataemia","status":"COMPLETED","sponsor":"Ineos Healthcare Limited","startDate":"2007-02","conditions":["Chronic Kidney Failure"],"enrollment":64,"completionDate":"2008-04"}],"genericFilers":[],"latestUpdates":[],"manufacturing":[],"crossReferences":{"NUI":"N0000179169","MMSL":"37251","NDDF":"001122","VUID":"4019975","VANDF":"4017711","RXNORM":"29164","UMLSCUI":"C0065527","ChEMBL_ID":"CHEMBL3989627","KEGG_DRUG":"D04836","DRUGBANK_ID":"DB13862","PUBCHEM_CID":"24439","MESH_SUPPLEMENTAL_RECORD_UI":"C030781"},"formularyStatus":[],"_enricherVersion":"v2","developmentCodes":[],"ownershipHistory":[],"publicationCount":849,"therapeuticAreas":["Other"],"atcClassification":{"source":"DrugCentral","atcCode":"B05XA10","allCodes":["B05XA10"]},"biosimilarFilings":[],"recentPublications":[{"date":"2026 Mar 11","pmid":"41900551","title":"A Novel Approach to Optimize the Rheology and Buildability of 3D-Printed Magnesium Phosphate Cement Composites Using Carbonated Recycled Aggregate.","journal":"Materials (Basel, Switzerland)"},{"date":"2026 Mar 27","pmid":"41894009","title":"A novel magnesium phosphate cement paste enables effective augmentation of pedicle screws in osteoporotic bone.","journal":"International orthopaedics"},{"date":"2026 Mar 9","pmid":"41893189","title":"Influence of Treated Surface Proportion on the Antibacterial Performance of UV-Activated Hydroxyapatite-Magnesium Phosphate-Zinc Oxide Coating on Magnesium Alloys.","journal":"Journal of functional biomaterials"},{"date":"2026","pmid":"41835087","title":"An all-in-one injectable biocement: self-setting magnesium phosphate for bone repair, fracture adhesion and osteoporotic fixation.","journal":"Regenerative biomaterials"},{"date":"2026 Mar 8","pmid":"41830278","title":"[Effects of Amendments and Straw Return on Soil and Rice Cd Content in a Rice/Rape Rotation System].","journal":"Huan jing ke xue= Huanjing kexue"}],"companionDiagnostics":[],"genericManufacturerList":[],"status":"active","companyName":"","companyId":"unknown","modality":"Small Molecule","firstApprovalDate":"","aiSummary":"Magnesium Orthophosphate, also known as magnesium phosphate, is a small molecule drug in the magnesium phosphate class. Its mechanism of action and approved indications are not well-documented, and it is unclear if it is FDA-approved or commercially available. As a result, there is limited information available on its safety profile, bioavailability, or half-life. Further research is needed to determine its potential therapeutic applications and commercial status. Without more information, it is difficult to provide a comprehensive summary of this compound.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"partial","dataCompleteness":{"mechanism":true,"indications":false,"safety":false,"trials":true,"score":2}}