{"id":"magnesium-gluconate","rwe":[],"tags":[{"label":"magnesium gluconate","category":"class"},{"label":"Small Molecule","category":"modality"},{"label":"A12CC03","category":"atc"},{"label":"Active","category":"status"},{"label":"Constipation","category":"indication"},{"label":"Hypomagnesemia","category":"indication"},{"label":"Incomplete passage of stool","category":"indication"},{"label":"Indigestion","category":"indication"}],"phase":"unknown","safety":{"safetySignals":[{"llr":131.141,"date":"","count":26,"signal":"Body tinea","source":"DrugCentral FAERS","actionTaken":"Reported 26 times (LLR=131)"},{"llr":122.442,"date":"","count":28,"signal":"Infection susceptibility increased","source":"DrugCentral FAERS","actionTaken":"Reported 28 times (LLR=122)"},{"llr":109.748,"date":"","count":26,"signal":"Inhibitory drug interaction","source":"DrugCentral FAERS","actionTaken":"Reported 26 times (LLR=110)"},{"llr":95.473,"date":"","count":27,"signal":"Glucose tolerance impaired","source":"DrugCentral FAERS","actionTaken":"Reported 27 times (LLR=95)"},{"llr":80.578,"date":"","count":27,"signal":"Bone density decreased","source":"DrugCentral FAERS","actionTaken":"Reported 27 times (LLR=81)"},{"llr":71.418,"date":"","count":28,"signal":"Poor quality sleep","source":"DrugCentral FAERS","actionTaken":"Reported 28 times (LLR=71)"},{"llr":71.363,"date":"","count":26,"signal":"Purpura","source":"DrugCentral FAERS","actionTaken":"Reported 26 times (LLR=71)"},{"llr":67.183,"date":"","count":28,"signal":"Hyperlipidaemia","source":"DrugCentral FAERS","actionTaken":"Reported 28 times (LLR=67)"},{"llr":66.811,"date":"","count":28,"signal":"Oral herpes","source":"DrugCentral FAERS","actionTaken":"Reported 28 times (LLR=67)"},{"llr":66.367,"date":"","count":24,"signal":"Impaired quality of life","source":"DrugCentral FAERS","actionTaken":"Reported 24 times (LLR=66)"},{"llr":61.141,"date":"","count":24,"signal":"Impaired work ability","source":"DrugCentral FAERS","actionTaken":"Reported 24 times (LLR=61)"},{"llr":60.915,"date":"","count":13,"signal":"Discoloured vomit","source":"DrugCentral FAERS","actionTaken":"Reported 13 times (LLR=61)"},{"llr":59.152,"date":"","count":9,"signal":"SARS-CoV-2 sepsis","source":"DrugCentral FAERS","actionTaken":"Reported 9 times (LLR=59)"},{"llr":53.49,"date":"","count":26,"signal":"Skin disorder","source":"DrugCentral FAERS","actionTaken":"Reported 26 times (LLR=53)"},{"llr":52.156,"date":"","count":32,"signal":"Cataract","source":"DrugCentral FAERS","actionTaken":"Reported 32 times (LLR=52)"}],"commonSideEffects":[{"effect":"Body tinea","drugRate":"LLR 131","severity":"common"},{"effect":"Infection susceptibility increased","drugRate":"LLR 122","severity":"common"},{"effect":"Inhibitory drug interaction","drugRate":"LLR 110","severity":"common"},{"effect":"Glucose tolerance impaired","drugRate":"LLR 95","severity":"common"},{"effect":"Bone density decreased","drugRate":"LLR 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gluconate","glucomag"],"timeline":[],"approvals":[],"brandName":"Glucomag","ecosystem":[{"indication":"Constipation","otherDrugs":[{"name":"bisacodyl","slug":"bisacodyl","company":"Braintree"},{"name":"cholic acid","slug":"cholic-acid","company":"Rtrx"},{"name":"docusate sodium","slug":"docusate-sodium","company":""},{"name":"glycerol","slug":"glycerol","company":"B Braun"}],"globalPrevalence":1120000000},{"indication":"Hypomagnesemia","otherDrugs":[{"name":"magnesium carbonate","slug":"magnesium-carbonate","company":"United Guardian"},{"name":"magnesium chloride","slug":"magnesium-chloride","company":"Hospira"},{"name":"magnesium oxide","slug":"magnesium-oxide","company":"Baxter Hlthcare"},{"name":"magnesium sulfate","slug":"magnesium-sulfate","company":"Baxter Hlthcare"}],"globalPrevalence":null},{"indication":"Incomplete passage of stool","otherDrugs":[{"name":"bisacodyl","slug":"bisacodyl","company":"Braintree"},{"name":"cholic acid","slug":"cholic-acid","company":"Rtrx"},{"name":"homatropine","slug":"homatropine","company":""},{"name":"macrogol","slug":"macrogol","company":"Braintree"}],"globalPrevalence":null},{"indication":"Indigestion","otherDrugs":[{"name":"algeldrate","slug":"algeldrate","company":"Sanofi Aventis Us"},{"name":"almasilate","slug":"almasilate","company":""},{"name":"bismuth subsalicylate","slug":"bismuth-subsalicylate","company":"Prometheus Labs"},{"name":"calcium carbonate","slug":"calcium-carbonate","company":"Mcneil Cons"}],"globalPrevalence":null}],"mechanism":{"modality":"Small Molecule","drugClass":"magnesium gluconate","explanation":"Think of magnesium like a key that helps your muscles and nerves work properly. When you're low on magnesium, your muscles can get stiff and your nerves can get a little mixed up. Glucomag helps to replace that magnesium, so your body can function normally again.","oneSentence":"Glucomag works by replenishing magnesium levels in the body, which helps to regulate muscle and nerve function.","technicalDetail":"Magnesium gluconate acts as a magnesium supplement, increasing serum magnesium levels and correcting magnesium deficiency, which is essential for muscle contraction, nerve conduction, and other physiological processes."},"_wikipedia":{"url":"https://en.wikipedia.org/wiki/Magnesium_gluconate","title":"Magnesium gluconate","extract":"Magnesium gluconate is a compound with formula Mg(C6H11O7)2. It is the magnesium salt of gluconic acid."},"commercial":{},"references":[{"id":1,"url":"https://drugcentral.org/drugcard/4515","fields":["approvals","synonyms","ATC","PK","indications","contraindications","DDIs","targets","patents","FAERS"],"source":"DrugCentral"},{"id":2,"url":"https://clinicaltrials.gov/search?intr=magnesium%20gluconate","fields":["trials"],"source":"ClinicalTrials.gov"},{"id":3,"url":"https://pubmed.ncbi.nlm.nih.gov/?term=magnesium gluconate","fields":["publications"],"source":"PubMed/NCBI"},{"id":4,"url":"https://en.wikipedia.org/wiki/Magnesium_gluconate","fields":["history","overview"],"source":"Wikipedia"}],"_enrichedAt":"2026-03-30T14:12:48.681017","biosimilars":[],"competitors":[{"drugName":"magnesium chloride","drugSlug":"magnesium-chloride","fdaApproval":"1975-08-13","relationship":"same-class"},{"drugName":"magnesium sulfate","drugSlug":"magnesium-sulfate","fdaApproval":"1981-10-06","genericCount":12,"patentStatus":"Off-patent — generic 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K Supplementation on Insomnia in Diabetics","status":"UNKNOWN","sponsor":"University of Lahore","startDate":"2020-10-26","conditions":["Focus of Study is on Insomnia Among Diabetic Patients"],"enrollment":320,"completionDate":"2022-04-26"},{"nctId":"NCT03054922","phase":"PHASE3","title":"Impact of Intraoperative Fluid Management on Electrolyte and Acid-base Variables","status":"COMPLETED","sponsor":"Nationwide Children's Hospital","startDate":"2017-02-23","conditions":["Anesthesia"],"enrollment":59,"completionDate":"2018-09-30"},{"nctId":"NCT02668952","phase":"PHASE2","title":"Fluid Chloride and AKI in Cardiopulmonary Bypass","status":"COMPLETED","sponsor":"University of New Mexico","startDate":"2016-01","conditions":["Acute Kidney Injury"],"enrollment":30,"completionDate":"2018-02"},{"nctId":"NCT02707549","phase":"PHASE2","title":"Fluid Therapy During Brain Tumor Resection in Children","status":"COMPLETED","sponsor":"Federal University of São Paulo","startDate":"2015-08","conditions":["Brain Neoplasms"],"enrollment":53,"completionDate":"2017-06"},{"nctId":"NCT01340690","phase":"PHASE3","title":"Efficacy Study of Polyunsaturated Fatty Acids in Children and Adolescents With Attention Deficit/ Hyperactivity Disorder","status":"TERMINATED","sponsor":"Johannes Gutenberg University Mainz","startDate":"2011-03-08","conditions":["ADHD"],"enrollment":284,"completionDate":"2017-03-01"},{"nctId":"NCT00316914","phase":"PHASE3","title":"Calcium Gluconate and Magnesium Sulfate in Preventing Neurotoxicity Caused By Oxaliplatin in Patients Receiving Combination Chemotherapy for Stage II, Stage III, or Stage IV Colorectal Cancer That Has Been Completely Removed By Surgery","status":"COMPLETED","sponsor":"Alliance for Clinical Trials in Oncology","startDate":"2006-01","conditions":["Colorectal Cancer","Neurotoxicity"],"enrollment":104,"completionDate":"2012-11"},{"nctId":"NCT00998738","phase":"PHASE3","title":"Calcium and Magnesium in Preventing Peripheral Neuropathy Caused by Ixabepilone in Patients With Breast Cancer","status":"TERMINATED","sponsor":"Mayo Clinic","startDate":"2009-11","conditions":["Neuropathy","Pain","Recurrent Breast Carcinoma","Stage IV Breast Cancer"],"enrollment":1,"completionDate":"2013-01"},{"nctId":"NCT01157052","phase":"PHASE1","title":"Oxaliplatin Pharmacokinetics With and Without Ca2+/MG2+ Infusion in Colorectal Cancer Patients","status":"UNKNOWN","sponsor":"AHS Cancer Control Alberta","startDate":"2015-01","conditions":["Neoplasms, Colorectal","Colorectal Cancer","Colorectal Carcinoma"],"enrollment":15,"completionDate":"2015-09"},{"nctId":"NCT01682499","phase":"PHASE1","title":"Calcium and Magnesium Infusion for the Prevention of Taxane Induced Neuropathy","status":"COMPLETED","sponsor":"Beth Israel Medical Center","startDate":"2012-08","conditions":["Paclitaxel-induced Neuropathy"],"enrollment":50,"completionDate":"2014-08"},{"nctId":"NCT01523574","phase":"PHASE2","title":"Vitamin E for Oxaliplatin-induced Peripheral Neuropathy Prophylaxis","status":"COMPLETED","sponsor":"Felipe Melo Cruz","startDate":"2009-08","conditions":["Peripheral Neuropathy"],"enrollment":38,"completionDate":"2010-12"},{"nctId":"NCT00007033","phase":"NA","title":"Study of Magnesium Sulfate in Children With Reduced Bone Density Secondary to Chronic Cholestatic Liver Disease","status":"COMPLETED","sponsor":"National Center for Research Resources (NCRR)","startDate":"2000-10","conditions":["Alagille Syndrome","Cholestasis","Biliary Atresia"],"enrollment":25,"completionDate":""}],"genericFilers":[],"latestUpdates":[],"manufacturing":[],"crossReferences":{"NUI":"N0000148148","MMSL":"5006","NDDF":"000787","UNII":"T42NAD2KHC","VUID":"4020251","VANDF":"4020249","RXNORM":"52358","UMLSCUI":"C0126777","ChEMBL_ID":"CHEMBL3989640","KEGG_DRUG":"D04835","DRUGBANK_ID":"DB13749","PUBCHEM_CID":"11418570","SECONDARY_CAS_RN":"59625-89-7","MESH_SUPPLEMENTAL_RECORD_UI":"C030691"},"formularyStatus":[],"_enricherVersion":"v2","developmentCodes":[],"ownershipHistory":[],"publicationCount":42,"therapeuticAreas":["Gastroenterology"],"atcClassification":{"source":"DrugCentral","atcCode":"A12CC03","allCodes":["A12CC03"]},"biosimilarFilings":[],"recentPublications":[],"companionDiagnostics":[],"genericManufacturerList":[],"status":"active","companyName":"","companyId":"unknown","modality":"Small Molecule","firstApprovalDate":"","aiSummary":"Glucomag, also known as magnesium gluconate, is a small molecule drug in the magnesium gluconate class. It is used to treat conditions such as constipation, hypomagnesemia, incomplete passage of stool, and indigestion. The commercial status of Glucomag is unknown, but it is likely available as a generic medication. Key safety considerations include potential gastrointestinal side effects. Glucomag is not FDA-approved for any indications.","enrichmentLevel":3,"visitCount":1,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}