{"id":"mabuterol","rwe":[],"tags":[{"label":"mabuterol","category":"class"},{"label":"Small Molecule","category":"modality"},{"label":"Active","category":"status"},{"label":"Adrenergic Agents","category":"pharmacology"},{"label":"Adrenergic Agonists","category":"pharmacology"},{"label":"Adrenergic beta-Agonists","category":"pharmacology"},{"label":"Anti-Asthmatic Agents","category":"pharmacology"},{"label":"Bronchodilator Agents","category":"pharmacology"},{"label":"Neurotransmitter Agents","category":"pharmacology"},{"label":"Peripheral Nervous System Agents","category":"pharmacology"},{"label":"Respiratory System Agents","category":"pharmacology"}],"phase":"phase_2","safety":{},"trials":[],"aliases":[],"patents":[],"pricing":[],"allNames":"ambuterol","offLabel":[],"synonyms":["broncholin","mabuterol","ambuterol","mabuterol hydrochloride","mabuterol HCl"],"timeline":[],"approvals":[],"brandName":"Ambuterol","ecosystem":[],"mechanism":{"modality":"Small Molecule","drugClass":"mabuterol","explanation":"Imagine your airways are like a narrow tube that gets constricted when you have asthma or COPD. Ambuterol helps to relax the muscles around this tube, making it easier to breathe. This is similar to how a bronchodilator inhaler works, but Ambuterol is a small molecule that can be taken orally or inhaled.","oneSentence":"Ambuterol is a bronchodilator that works by relaxing the muscles in the airways to improve breathing.","technicalDetail":"Ambuterol is a beta-2 adrenergic receptor agonist that activates the Gs protein-coupled receptor, leading to an increase in cAMP and relaxation of airway smooth muscle."},"commercial":{},"references":[{"id":1,"url":"https://drugcentral.org/drugcard/1623","fields":["approvals","synonyms","ATC","PK","indications","contraindications","DDIs","targets","patents","FAERS"],"source":"DrugCentral"},{"id":2,"url":"https://pubmed.ncbi.nlm.nih.gov/?term=MABUTEROL","fields":["publications"],"source":"PubMed/NCBI"}],"_enrichedAt":"2026-03-30T12:27:41.015179","biosimilars":[],"competitors":[],"genericName":"mabuterol","indications":{"approved":[],"offLabel":[],"pipeline":[]},"drugCategory":"active","labelChanges":[],"relatedDrugs":[],"trialDetails":[],"genericFilers":[],"latestUpdates":[],"manufacturing":[],"crossReferences":{"NDDF":"008207","UNII":"R4K19W6S7Q","CHEBI":"CHEBI:135325","INN_ID":"5089","UMLSCUI":"C0065464","ChEMBL_ID":"CHEMBL86749","KEGG_DRUG":"D01589","PUBCHEM_CID":"3995","SECONDARY_CAS_RN":"54240-36-7","MESH_SUPPLEMENTAL_RECORD_UI":"C044573"},"formularyStatus":[],"_enricherVersion":"v2","developmentCodes":[],"ownershipHistory":[],"publicationCount":75,"therapeuticAreas":["Respiratory"],"biosimilarFilings":[],"recentPublications":[],"companionDiagnostics":[],"genericManufacturerList":[],"status":"active","companyName":"","companyId":"","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Ambuterol, also known as Mabuterol, is a small molecule drug of the mabuterol class. Its target and exact mechanism of action are unknown. It is not FDA-approved for any indications. The commercial status of Ambuterol is unclear, and it may be patented or generic. Key safety considerations are also unknown.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"partial","dataCompleteness":{"mechanism":true,"indications":false,"safety":false,"trials":false,"score":1}}