{"id":"m207-microneedle-system","safety":{"commonSideEffects":[{"rate":null,"effect":"Skin irritation at application site"},{"rate":null,"effect":"Erythema"},{"rate":null,"effect":"Pruritus"}]},"_chembl":null,"_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"The M207 microneedle system uses an array of tiny, solid microneedles to create transient pathways through the stratum corneum, enabling delivery of therapeutic molecules that would otherwise be poorly absorbed through intact skin. This approach bypasses hepatic first-pass metabolism and allows for sustained or controlled release of drugs. The technology platform is being developed to deliver various pharmaceutical agents, with initial focus on peptides and proteins.","oneSentence":"M207 is a microneedle patch system designed to deliver drugs transdermally by piercing the skin barrier with microscopic needles.","_ai_confidence":"medium"},"_scrapedAt":"2026-03-28T00:49:43.016Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Migraine (zolmitriptan delivery via microneedle patch)"}]},"trialDetails":[{"nctId":"NCT03282227","phase":"PHASE3","title":"A Study to Evaluate the Long-Term Safety of M207 in the Acute Treatment of Migraine","status":"COMPLETED","sponsor":"Zosano Pharma Corporation","startDate":"2017-11-07","conditions":"Migraine","enrollment":342}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":1,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":["ZP-Zolmitriptan Intracutaneous Microneedle System","ADAM-Zolmitriptan"],"phase":"phase_3","status":"active","brandName":"M207 Microneedle System","genericName":"M207 Microneedle System","companyName":"Zosano Pharma Corporation","companyId":"zosano-pharma-corporation","modality":"Small molecule","firstApprovalDate":"","aiSummary":"M207 is a microneedle patch system designed to deliver drugs transdermally by piercing the skin barrier with microscopic needles. Used for Migraine (zolmitriptan delivery via microneedle patch).","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":1,"withResults":1},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}