{"id":"m-m-rtm-ii","safety":{"commonSideEffects":[{"rate":"5-15","effect":"Fever"},{"rate":"5","effect":"Rash"},{"rate":"<1","effect":"Parotitis (mumps-like symptoms)"},{"rate":"1-3","effect":"Arthralgia/arthritis"},{"rate":"<1","effect":"Thrombocytopenia"},{"rate":"10-20","effect":"Local injection site reactions"}]},"_chembl":null,"_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"The vaccine contains live but weakened (attenuated) strains of measles, mumps, and rubella viruses. When administered, these attenuated viruses replicate in the body at low levels, triggering both humoral (antibody) and cell-mediated immune responses without causing disease. This generates protective immunity against all three viral infections.","oneSentence":"M-M-R II is a live attenuated viral vaccine that stimulates immune responses against measles, mumps, and rubella by introducing weakened forms of these viruses.","_ai_confidence":"high"},"_scrapedAt":"2026-03-27T23:53:45.786Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Prevention of measles, mumps, and rubella in children and adults"}]},"trialDetails":[{"nctId":"NCT00432731","phase":"PHASE4","title":"Safety Study of a Refrigerator-stable Formulation of VARIVAX®","status":"COMPLETED","sponsor":"Merck Sharp & Dohme LLC","startDate":"2004-12","conditions":"Varicella, Measles, Mumps","enrollment":500}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":1316564,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":[],"phase":"marketed","status":"active","brandName":"M-M-RTM II","genericName":"M-M-RTM II","companyName":"Merck Sharp & Dohme LLC","companyId":"merck","modality":"Biologic","firstApprovalDate":"","aiSummary":"M-M-RTM II is a vaccine used to prevent Varicella, Measles, Mumps, and Rubella. It is a formulation of VARIVAX, a vaccine that has been studied for safety in a clinical trial.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}