{"id":"lutinus-transfer-day-7","safety":{"commonSideEffects":[{"rate":null,"effect":"Vaginal irritation or discharge"},{"rate":null,"effect":"Headache"},{"rate":null,"effect":"Breast tenderness"},{"rate":null,"effect":"Abdominal discomfort"}]},"_chembl":{"chemblId":"CHEMBL1230575","moleculeType":"Small molecule","molecularWeight":"649.02"},"_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"Lutinus (micronized progesterone) provides exogenous progesterone to supplement endogenous production during the luteal phase after ovulation or embryo transfer. Progesterone is essential for endometrial preparation and maintenance of early pregnancy, particularly in assisted reproduction where luteal phase support may be inadequate. Administration on transfer day 7 (or similar timing) helps ensure adequate progesterone levels during the critical window of embryo implantation and early pregnancy establishment.","oneSentence":"Lutinus is a progesterone supplement used to support luteal phase function and embryo implantation during assisted reproductive technology cycles.","_ai_confidence":"medium"},"_scrapedAt":"2026-03-27T23:53:34.431Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Luteal phase support in assisted reproductive technology (ART) cycles"},{"name":"Embryo transfer support in in vitro fertilization (IVF)"}]},"trialDetails":[{"nctId":"NCT03795220","phase":"PHASE4","title":"Preparing and Timing of the Endometrium in Modified Natural Cycle Frozen-thawed Embryo Transfers","status":"COMPLETED","sponsor":"Anja Bisgaard Pinborg","startDate":"2019-01-06","conditions":"Infertility","enrollment":679},{"nctId":"NCT04725864","phase":"PHASE4","title":"Progesterone as Luteal Support in Frozen IVF Natural Cycles","status":"RECRUITING","sponsor":"Vastra Gotaland Region","startDate":"2021-05-01","conditions":"Infertility, Embryo Transfer","enrollment":1800}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":0,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":["Lutinus"],"phase":"marketed","status":"active","brandName":"Lutinus + transfer day 7","genericName":"Lutinus + transfer day 7","companyName":"Anja Bisgaard Pinborg","companyId":"anja-bisgaard-pinborg","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Lutinus is a progesterone supplement used to support luteal phase function and embryo implantation during assisted reproductive technology cycles. Used for Luteal phase support in assisted reproductive technology (ART) cycles, Embryo implantation support in in vitro fertilization (IVF).","enrichmentLevel":3,"visitCount":1,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}