{"id":"loxonine-tab","safety":{"commonSideEffects":[{"rate":null,"effect":"Bleeding"},{"rate":null,"effect":"Gastrointestinal disturbance"},{"rate":null,"effect":"Headache"}]},"_chembl":null,"_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"Loxonine functions as an antiplatelet and anticoagulant agent. Upon absorption, it is metabolized to an active metabolite that inhibits platelet function and reduces thrombotic risk. The exact molecular mechanism involves interference with platelet activation pathways, making it useful in cardiovascular and thromboembolic conditions.","oneSentence":"Loxonine is a prodrug that is converted to its active form to inhibit platelet aggregation and provide anticoagulant effects.","_ai_confidence":"low"},"_scrapedAt":"2026-03-28T01:19:41.145Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Thrombotic disorders"},{"name":"Stroke prevention"},{"name":"Peripheral arterial disease"}]},"trialDetails":[{"nctId":"NCT03386149","phase":"PHASE3","title":"Clinical Research on the Efficacy of Bosinji on Herniated Intervertebral Disc of Lumbar Spine","status":"COMPLETED","sponsor":"Kyunghee University Medical Center","startDate":"2017-12-28","conditions":"Lumbar Disc Herniation","enrollment":74}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":5873,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":["Loxoprofen"],"phase":"phase_3","status":"active","brandName":"Loxonine tab.","genericName":"Loxonine tab.","companyName":"Kyunghee University Medical Center","companyId":"kyunghee-university-medical-center","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Loxonine is a prodrug that is converted to its active form to inhibit platelet aggregation and provide anticoagulant effects. Used for Thrombotic disorders, Stroke prevention, Peripheral arterial disease.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":1,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}