{"id":"low-molecular-weight-iron-dextran","safety":{"commonSideEffects":[{"rate":null,"effect":"Injection site reactions (pain, discoloration)"},{"rate":null,"effect":"Hypersensitivity reactions"},{"rate":null,"effect":"Headache"},{"rate":null,"effect":"Arthralgia"},{"rate":null,"effect":"Fever"}]},"_chembl":null,"_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"Iron dextran is a colloidal complex of ferric hydroxide and dextran that allows parenteral iron delivery. The low molecular weight formulation has improved pharmacokinetics and reduced immunogenicity compared to higher molecular weight versions, enabling more efficient cellular uptake of iron for hemoglobin synthesis and correction of iron deficiency states.","oneSentence":"Low molecular weight iron dextran delivers iron directly into cells to replenish iron stores and treat iron deficiency anemia.","_ai_confidence":"medium"},"_scrapedAt":"2026-03-27T23:53:35.924Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Iron deficiency anemia in patients unable to tolerate or absorb oral iron"},{"name":"Iron deficiency anemia in chronic kidney disease patients on hemodialysis"}]},"trialDetails":[{"nctId":"NCT05340465","phase":"PHASE2","title":"Darbe Plus IV Iron to Decrease Transfusions While Maintaining Iron Sufficiency in Preterm Infants","status":"RECRUITING","sponsor":"University of Washington","startDate":"2022-11-27","conditions":"Prematurity, Iron-deficiency, Iron Deficiency Anemia","enrollment":120},{"nctId":"NCT05292001","phase":"PHASE4","title":"Single-dose Intravenous Iron Therapy for Anemia After Orthopaedic Trauma","status":"RECRUITING","sponsor":"Oregon Health and Science University","startDate":"2022-06-01","conditions":"Acute Blood Loss Anemia, Fracture","enrollment":150},{"nctId":"NCT02889133","phase":"NA","title":"Donor Iron Deficiency Study - Red Blood Cells From Iron-deficient Donors: Recovery and Storage Quality","status":"COMPLETED","sponsor":"Columbia University","startDate":"2017-01","conditions":"Iron Deficiency","enrollment":79},{"nctId":"NCT05047211","phase":"PHASE4","title":"Intravenous Iron vs. Oral Iron Supplementation for Postpartum Anemia","status":"COMPLETED","sponsor":"The University of Texas Medical Branch, Galveston","startDate":"2021-10-07","conditions":"Anemia, Iron Deficiency, Delivery Complication","enrollment":40},{"nctId":"NCT02038023","phase":"PHASE2","title":"Intravaneous Iron(1000 mg Low Molecular Weight Iron Dextran Over 60 Minutes) for Pregnant Women","status":"COMPLETED","sponsor":"Auerbach Hematology Oncology Associates P C","startDate":"2013-07","conditions":"Pregnancy","enrollment":74},{"nctId":"NCT02086838","phase":"PHASE4","title":"Iron Supplementation Using Total Dose Infusion and Oral Routes for Treatment of Iron Deficiency Anemia in Pregnancy","status":"COMPLETED","sponsor":"Ain Shams University","startDate":"2013-07","conditions":"Treatment of Iron Deficiency Anemia in Pregnancy","enrollment":212}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":76,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":["INFeD","LMW-ID","Cosmofer"],"phase":"marketed","status":"active","brandName":"Low Molecular Weight Iron Dextran","genericName":"Low Molecular Weight Iron Dextran","companyName":"University of Washington","companyId":"university-of-washington","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Low molecular weight iron dextran delivers iron directly into cells to replenish iron stores and treat iron deficiency anemia. Used for Iron deficiency anemia in patients who cannot tolerate or have failed oral iron therapy.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}