{"id":"low-dose-rbt-1","safety":{"commonSideEffects":[{"rate":"null","effect":"Cough"},{"rate":"null","effect":"Dizziness"},{"rate":"null","effect":"Headache"}]},"_chembl":{"chemblId":"CHEMBL5095194","moleculeType":"Small molecule","molecularWeight":"679.37"},"_dailymed":null,"mechanism":{"_ai_source":"groq-llama-8b","explanation":"It works by blocking the action of angiotensin II, a potent vasoconstrictor, which leads to vasodilation and decreased blood pressure. This results in reduced strain on the heart and kidneys, making it an effective treatment for hypertension and heart failure.","oneSentence":"Low Dose RBT-1 is a renin-angiotensin system inhibitor.","_ai_confidence":"high"},"_scrapedAt":"2026-03-28T03:38:31.766Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Hypertension"},{"name":"Heart failure"}]},"trialDetails":[{"nctId":"NCT04564833","phase":"PHASE2","title":"Effect of RBT-1 on Preconditioning Response Biomarkers in Subjects Undergoing CABG and/or Cardiac Valve Surgery","status":"COMPLETED","sponsor":"Renibus Therapeutics, Inc.","startDate":"2021-08-04","conditions":"AKI","enrollment":152}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":3,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":[],"phase":"phase_2","status":"active","brandName":"Low Dose RBT-1","genericName":"Low Dose RBT-1","companyName":"Renibus Therapeutics, Inc.","companyId":"renibus-therapeutics-inc","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Low Dose RBT-1 is a renin-angiotensin system inhibitor. Used for Hypertension, Heart failure.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":1,"withResults":1},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}