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The mucosal replication site provides direct stimulation of respiratory tract immunity, which is particularly relevant for preventing influenza infection at the site of viral entry.","oneSentence":"This vaccine contains live but weakened influenza viruses that replicate in the nasal mucosa to stimulate both mucosal and systemic immune responses without causing disease.","_ai_confidence":"medium"},"_scrapedAt":"2026-03-27T23:52:46.537Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Influenza prevention in children and adults"}]},"trialDetails":[{"nctId":"NCT05921448","phase":"EARLY_PHASE1","title":"Vaccine Pandemic Preparedness Through Airway Immunology Characterization","status":"ACTIVE_NOT_RECRUITING","sponsor":"Copenhagen Respiratory Research","startDate":"2025-05-19","conditions":"Influenza, Human","enrollment":60},{"nctId":"NCT04901455","phase":"EARLY_PHASE1","title":"Responses to Live Attenuated Influenza Virus (LAIV) in Chronic Obstructive 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