{"id":"lipoplus-20","safety":{"commonSideEffects":[{"rate":null,"effect":"Hypertriglyceridemia"},{"rate":null,"effect":"Infusion site reactions"},{"rate":null,"effect":"Allergic reactions"},{"rate":null,"effect":"Lipemia"}]},"_chembl":{"chemblId":"CHEMBL3646171","moleculeType":"Small molecule","molecularWeight":"408.51"},"_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"This intravenous lipid emulsion supplies long-chain triglycerides (LCTs) derived from soybean oil, providing both energy (9 kcal/g) and essential polyunsaturated fatty acids (linoleic and alpha-linolenic acid) necessary for cell membrane integrity and metabolic function. It is used as part of total parenteral nutrition (TPN) regimens to prevent essential fatty acid deficiency and support nutritional requirements in critically ill or post-operative patients.","oneSentence":"Lipoplus 20% is a lipid emulsion that provides essential fatty acids and calories for parenteral nutrition in patients unable to eat orally.","_ai_confidence":"medium"},"_scrapedAt":"2026-03-27T23:52:29.297Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Parenteral nutrition in patients unable to maintain adequate oral/enteral intake"},{"name":"Prevention of essential fatty acid deficiency in long-term parenteral nutrition"}]},"trialDetails":[{"nctId":"NCT03282955","phase":"PHASE4","title":"The HOME Study (HPN With OMEGA-3)","status":"COMPLETED","sponsor":"B. Braun Melsungen AG","startDate":"2018-01-08","conditions":"Patients Requiring Home Parenteral Nutrition","enrollment":74},{"nctId":"NCT03149653","phase":"PHASE4","title":"Crossover Study on the Effect of Omegaven in Combination With Different Lipid Emulsions in Home Parenteral Nutrition","status":"COMPLETED","sponsor":"General University Hospital, Prague","startDate":"2012-01-15","conditions":"Parenteral Nutrition","enrollment":24},{"nctId":"NCT01814956","phase":"PHASE4","title":"Different Lipid Emulsions in Acute Lung Injury Patients","status":"TERMINATED","sponsor":"B. Braun Melsungen AG","startDate":"2013-03","conditions":"Parenteral Nutrition","enrollment":1},{"nctId":"NCT00396461","phase":"PHASE4","title":"ICULIP, Influence of Two Lipid Emulsions in the Nosocomial Infection in Critical Patients","status":"TERMINATED","sponsor":"B. Braun Medical SA","startDate":"2006-11","conditions":"Critical Illness","enrollment":212}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":3,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":[],"phase":"marketed","status":"active","brandName":"Lipoplus 20%","genericName":"Lipoplus 20%","companyName":"B. Braun Melsungen AG","companyId":"b-braun-melsungen-ag","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Lipoplus 20% is a lipid emulsion that provides essential fatty acids and calories for parenteral nutrition in patients unable to take oral or enteral nutrition. Used for Parenteral nutrition support in patients unable to receive adequate oral or enteral nutrition, Provision of essential fatty acids and energy in critically ill or post-operative patients.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}