{"id":"lipocol-forte-capsules","safety":{"commonSideEffects":[{"rate":null,"effect":"Myalgia"},{"rate":null,"effect":"Elevated liver enzymes"},{"rate":null,"effect":"Gastrointestinal disturbance"},{"rate":null,"effect":"Headache"}]},"_chembl":null,"_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"LipoCol Forte is a combination lipid-lowering formulation that typically contains a statin (such as lovastatin or simvastatin) along with other cholesterol-reducing agents. The statin component inhibits HMG-CoA reductase, the rate-limiting enzyme in cholesterol synthesis, thereby reducing LDL cholesterol production. Additional components may work synergistically to enhance HDL cholesterol and reduce triglycerides through complementary mechanisms.","oneSentence":"LipoCol Forte reduces cholesterol levels by inhibiting HMG-CoA reductase and enhancing cholesterol clearance through multiple lipid-lowering pathways.","_ai_confidence":"medium"},"_scrapedAt":"2026-03-27T23:52:30.759Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Hypercholesterolemia"},{"name":"Dyslipidemia"},{"name":"Cardiovascular disease prevention"}]},"trialDetails":[{"nctId":"NCT06301906","phase":"","title":"Red Yeast Rice for Primary Prevention of Hypercholesterolemia","status":"COMPLETED","sponsor":"Chang Gung Memorial Hospital","startDate":"2024-02-26","conditions":"Hypercholesterolemia","enrollment":41},{"nctId":"NCT01527669","phase":"PHASE4","title":"The Pharmacokinetic Study of Red Yeast Rice Capsule Compared to Lovastatin Tablet in Healthy Subjects","status":"COMPLETED","sponsor":"National Taiwan University Hospital","startDate":"2012-02","conditions":"Healthy Subjects","enrollment":12},{"nctId":"NCT01269762","phase":"PHASE4","title":"Pharmacokinetic and Drug Interaction Study of Red Yeast Rice Capsules","status":"COMPLETED","sponsor":"National Taiwan University Hospital","startDate":"2011-01","conditions":"Healthy Volunteer","enrollment":14},{"nctId":"NCT01346657","phase":"PHASE4","title":"The Effect of LipoCol Forte® Capsules on the Pharmacokinetics of Nifedipine After Administering Single-dose Combination to Healthy Subjects","status":"COMPLETED","sponsor":"Taipei Medical University WanFang Hospital","startDate":"2009-07","conditions":"Healthy Volunteers","enrollment":14},{"nctId":"NCT01346670","phase":"PHASE4","title":"Lovastatin and Its ß-hydroxy Acid From Four 600 mg LipoCol Forte® Capsules Compared to That of One 20 mg Mevacor® Tablet in Healthy Subjects","status":"COMPLETED","sponsor":"Taipei Medical University WanFang Hospital","startDate":"2006-10","conditions":"Healthy Volunteer","enrollment":14}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":2,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":[],"phase":"marketed","status":"active","brandName":"LipoCol Forte capsules","genericName":"LipoCol Forte capsules","companyName":"National Taiwan University Hospital","companyId":"national-taiwan-university-hospital","modality":"Small molecule","firstApprovalDate":"","aiSummary":"LipoCol Forte reduces cholesterol levels by inhibiting HMG-CoA reductase and enhancing cholesterol clearance through multiple lipid-lowering pathways. Used for Hypercholesterolemia, Dyslipidemia, Cardiovascular disease prevention.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}