{"id":"liothyronine-and-levothyroxine","safety":{"commonSideEffects":[{"rate":null,"effect":"Tachycardia"},{"rate":null,"effect":"Tremor"},{"rate":null,"effect":"Anxiety"},{"rate":null,"effect":"Insomnia"},{"rate":null,"effect":"Heat intolerance"},{"rate":null,"effect":"Palpitations"}]},"_chembl":null,"_dailymed":{"setId":"40fa228f-9bfc-fc71-e063-6394a90a9ab6","title":"EVEXITHROID (LEVOTHYROXINE AND LIOTHYRONINE) TABLET [TRIFLUENT PHARMA, LLC]"},"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"Levothyroxine is converted peripherally to the more active liothyronine (T3), which enters cells and binds to thyroid hormone receptors in the nucleus, modulating gene expression related to metabolism, thermogenesis, and cardiovascular function. 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