{"id":"lidocaine-patch-local-application","rwe":[],"tags":[],"safety":{"boxedWarnings":[],"drugInteractions":[],"commonSideEffects":[{"effect":"Application site reactions","drugRate":"10-20%","severity":"Mild to moderate"},{"effect":"Redness","drugRate":"5-10%","severity":"Mild"},{"effect":"Itching","drugRate":"5-10%","severity":"Mild"},{"effect":"Swelling","drugRate":"2-5%","severity":"Mild"}],"contraindications":["Hypersensitivity to lidocaine or other amide-type local anesthetics"],"specialPopulations":{}},"trials":[],"_chembl":{"chemblId":"CHEMBL79","moleculeType":"Small molecule","molecularWeight":"234.34"},"aliases":["Lidopat patch"],"patents":[],"pricing":[{"market":"United States","source":"CMS National Average Drug Acquisition Cost (NADAC)","asOfDate":"2024-01-03","unitCost":"$0.0934/ML","priceType":"NADAC","sourceUrl":"https://data.medicaid.gov/dataset/4j6z-xnwq","annualCost":"$34","description":"LIDOCAINE 2% VISCOUS SOLN","retrievedDate":"2026-04-07"}],"offLabel":[],"timeline":[],"_dailymed":null,"aiSummary":"The Lidocaine patch is a local anesthetic used for the management of pain associated with post-herpetic neuralgia. It is applied topically to the skin and works by blocking sodium channels in nerve cells, thereby reducing pain signals. The patch is manufactured by Taipei Medical University Hospital and does not have an FDA label. Common side effects include application site reactions, such as redness, itching, and swelling. The drug is generally well-tolerated but has specific contraindications and warnings.","ecosystem":[],"mechanism":{"target":"Sodium channels","novelty":"The lidocaine patch provides a targeted, non-systemic delivery method for pain relief, reducing systemic side effects.","modality":"Topical","drugClass":"Local anesthetic","explanation":"Lidocaine is a local anesthetic that acts by inhibiting the influx of sodium ions into nerve cells, which prevents the generation and propagation of action potentials.","oneSentence":"Lidocaine patch works by locally blocking sodium channels in nerve cells, which reduces the transmission of pain signals.","technicalDetail":"Lidocaine binds to the intracellular portion of the sodium channel, stabilizing the inactivated state of the channel and preventing it from opening, thus blocking the conduction of pain signals."},"_scrapedAt":"2026-03-27T23:52:12.556Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"commercial":{"yoyGrowth":null,"launchDate":null,"annualCostUS":null,"currentRevenue":null,"patientPopulation":null,"peakSalesEstimate":null},"references":[],"biosimilars":[],"competitors":[],"dataSources":[{"url":"https://data.medicaid.gov/dataset/4j6z-xnwq","name":"CMS National Average Drug Acquisition Cost (NADAC)","fields":["pricing"],"retrievedDate":"2026-04-07"}],"indications":{"approved":["Post-herpetic neuralgia"],"offLabel":[],"pipeline":[]},"labelChanges":[],"relatedDrugs":[],"trialDetails":[{"nctId":"NCT07354464","phase":"PHASE3","title":"Efficacy of Sphenopalatine Block Compared to Blood Patch in the Management of Post-dural Puncture Headaches","status":"RECRUITING","sponsor":"University Hospital, Clermont-Ferrand","startDate":"2026-02-19","conditions":"PDPH, Post Dural Puncture Headache","enrollment":80},{"nctId":"NCT06726434","phase":"NA","title":"Evaluation of 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Hospital","startDate":"2021-08-09","conditions":"Procedure, Gynecologic Surgical","enrollment":248},{"nctId":"NCT05587075","phase":"NA","title":"Clinical Effect of Long Round Needle","status":"COMPLETED","sponsor":"Zhanqing Xie","startDate":"2020-01-01","conditions":"Cervical Spondylotic Radiculopathy","enrollment":98},{"nctId":"NCT05187494","phase":"NA","title":"Enhancing the Efficiency of EMLA Cream in Palatal Anesthesia for Children","status":"COMPLETED","sponsor":"Damascus University","startDate":"2021-05-20","conditions":"Extrusion of Tooth","enrollment":75},{"nctId":"NCT03096457","phase":"PHASE2, PHASE3","title":"Topical Paromomycin for Cutaneous Leishmaniasis in Bolivia","status":"COMPLETED","sponsor":"Fundacion Nacional de Dermatologia","startDate":"2017-04-15","conditions":"Leishmaniasis, Cutaneous, Leishmania Braziliensis Complex, Leishmaniasis, American","enrollment":80},{"nctId":"NCT02996097","phase":"NA","title":"Fractional Laser Assisted Steroid Therapy vs Intralesional Steroids in the Treatment of Keloids","status":"COMPLETED","sponsor":"Johns Hopkins University","startDate":"2016-04","conditions":"Keloid","enrollment":30},{"nctId":"NCT03587220","phase":"NA","title":"A Mechanistic Evaluation of the Nociceptive Desensitizing Properties of Topical Capsaicin","status":"COMPLETED","sponsor":"Aalborg University","startDate":"2018-08-01","conditions":"Capsaicin, Ultaviolet B Light Burn, Neuropathic Pain","enrollment":44},{"nctId":"NCT03629041","phase":"PHASE1","title":"A Study of the Use of Microneedle Patches to Deliver Topical Lidocaine in the Oral Cavity","status":"COMPLETED","sponsor":"Innoture Ltd","startDate":"2018-07-31","conditions":"Topical Anaesthesia","enrollment":16},{"nctId":"NCT04026074","phase":"PHASE4","title":"Concepts for Analgosedation During Placement of Regional Anaesthesia Before Operations.","status":"COMPLETED","sponsor":"Medical University of Graz","startDate":"2019-07-26","conditions":"Knee Arthropathy, Hip Arthritis, Fractures, 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Pain","enrollment":60}],"_emaApprovals":[],"_faersSignals":[],"genericFilers":[],"latestUpdates":[],"manufacturing":[],"formularyStatus":[],"_approvalHistory":[],"developmentCodes":[],"ownershipHistory":[],"publicationCount":3,"therapeuticAreas":["Pain"],"biosimilarFilings":[],"companionDiagnostics":[],"genericManufacturerList":[],"phase":"marketed","status":"active","brandName":"Lidocaine patch local application","genericName":"Lidocaine patch local application","companyName":"Taipei Medical University Hospital","companyId":"taipei-medical-university-hospital","modality":"Small molecule","firstApprovalDate":"","enrichmentLevel":3,"visitCount":0,"regulatoryByCountry":[{"country_code":"CA","regulator":"Health 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